Volume 24, Issue 3, Pages 205-211 (September 2017) H. pylori infection increases gastric mucosal COX2 and mTOR expression in chronic gastritis: Implications for cancer progression?  Dalia M. Badary, Mohammed Zakaria Ali Abu Rahma, Ahmed M. Ashmawy, Mohamed Z. Hafez  Pathophysiology  Volume 24, Issue 3, Pages 205-211 (September 2017) DOI: 10.1016/j.pathophys.2017.05.004 Copyright © 2017 Elsevier B.V. Terms and Conditions

Fig. 1 Gastric sections from H. pylori associated chronic gastritis patients immunostained with mTOR and COX2 molecular markers (200x). (A) shows negative expression of mTOR in mildly inflamed gastric mucosa with mild H. pylori colonization, Fig. 1(B) shows weak expression of COX2 in mildly inflamed gastric mucosa mild H. pylori colonization, Fig1(C) and 1(D) show moderate expression of mTOR and COX2 respectively in H. pylori associated chronic gastritis with moderate amount of H. pylori colonization and moderate inflammatory response, Fig. 1(E) and Fig. 1(F) show strong expression of mTOR and COX2 respectively in H. pylori associated chronic gastritis with extensive chronic inflammation associated with multiple lymphoid follicles formation. Pathophysiology 2017 24, 205-211DOI: (10.1016/j.pathophys.2017.05.004) Copyright © 2017 Elsevier B.V. Terms and Conditions

Fig. 2 Gastric sections from H. pylori associated chronic gastritis patients immunostained with mTOR and COX2 molecular markers (200x). (A) and (B) show strong expression of mTOR and COX2 respectively in H. pylori associated chronic gastritis with severe paneth cell metaplasia and Fig. 2(C) and Fig. 2(D) show strong expression of mTOR and COX2 respectively in H. pylori associated chronic gastritis with severe goblet cell metaplasia and low-grade dysplasia. Pathophysiology 2017 24, 205-211DOI: (10.1016/j.pathophys.2017.05.004) Copyright © 2017 Elsevier B.V. Terms and Conditions