Chapter 87: Orthopedic Treatment of Metastatic Bone Disease Kristy Weber and Scott Kominsky

From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Figure 1 Figure 1 This schematic shows the general cycle of bone destruction (osteolytic metastasis–lung cancer) and bone formation (osteoblastic metastasis–breast cancer). Figure 1 This schematic shows the general cycle of bone destruction (osteolytic metastasis–lung cancer) and bone formation (osteoblastic metastasis–breast cancer). © 2008 American Society for Bone and Mineral Research

From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Figure 2 Figure 2 (A) A radiograph of the right proximal femur in an 82-yr-old woman with metastatic breast cancer shows an osteolytic lesion in the subtrochanteric region at high risk for pathologic fracture. (B) Postoperative radiograph showing the stabilization of the femur with an intramedullary reconstruction nail. Figure 2 (A) A radiograph of the right proximal femur in an 82-yr-old woman with metastatic breast cancer shows an osteolytic lesion in the subtrochanteric region at high risk for pathologic fracture. (B) Postoperative radiograph showing the stabilization of the femur with an intramedullary reconstruction nail. © 2008 American Society for Bone and Mineral Research