Robert Wartenberg MD Robert Fishman MD Robert B Layzer MD History of Neurology West Coast Neurology ________________________________ The 3 Roberts of UCSF Robert Wartenberg MD Robert Fishman MD Robert B Layzer MD

Robert Wartenberg MD (1887-1956) b Garten (German border of Russia) Schooling: Gymnasium in Stuttgart Medical studies: U of Kiel, Munich, Freiburg, and Rostock. (grad 1919) Mentors: Hocke (Freiburg) Cassier (Berlin) Nonne (Hamburg) Foerster (Breslau) 1925: Fellow Rockefeller Foundation- England/France/USA (Boston under Cushing) 1928- Privatdozent in Freiburg 1933-Head Neurology Clinic Freiburg 1935-Fled Nazi Germany to USA & UCSF- rose through academic ranks 1952- Clin Prof Neurology/ 1954 Prof Emeritus

Robert Wartenberg MD (1887-1956) Link to golden age of descriptive Neurology in Europe Books: Examinations of Reflexes and Diagnostic Test of Neurology (1945) Diagnostic Tests of Neurology (1953) Neuritis, Sensory Neuritis, Neuralgia (1958) Wartenberg’s Eponymy’s Disseminated sensory neuropathy of Wartenberg Wartenberg syndrome or cheiralgia paraesthetica – radial sensory neuropathy Sign of Wartenberg –abduction of 5th finger in ulnar nerve palsy Phenomenon of Wartenberg – deviation of jaw of opposite side when touch cornea-also cornea mandibular reflex Roulette Wartenberg- sensory testing device

Wartenberg’s Sign- Associated Movement of the Thumb Patients palm up on examiners hand Flex fingers against examiners fingers Normally – no thumb movement Pyramidal lesion– thumb abduct , flex, cross palm in opposition Variant- hook top patients index finger against examiners

Wartenberg Wheel A Wartenberg wheel, also called a Wartenberg pinwheel or Wartenberg neurowheel, is a medical device for neurological use. Robert Wartenberg designed the wheel to test nerve reactions (sensitivity) as it rolled systematically across the skin.

Robert Fishman MD 1924-2012 b NYC College :Columbia, age 16; med school: U Penn Accelerated US Army program in WWII- grad 1947, age 22 Intern- Yale; then MGH Then Columbia for Neuro residency co-residents: Ziegler & Rowland ; mentor/chair: H Houston Merritt Korean War- Walter Reed Hos Chief Res & Faculty Columbia Studied blood-brain barrier & CSF physiology and biochemistry 1966 UCSF-Chair Neuro until 1992 Pres AAN,AUPN, ANA, ABPN Editor: Annals of Neurology

Lewis “Bud” Rowland, Dewey Ziegler & Robert Fishman . Robert Fishman & Dewey Ziegler

Robert Fishman MD 1924-2012 Cerebrospinal Fluid in Diseases of the Nervous System (1980 1ST ed, 2nd ed. 1992) Was continuation of H. Houston Merritt’s book - Cerebrospinal Fluid (1938) Cerebrospinal Fluid in Diseases of the Nervous System Cerebrospinal Fluid 2nd Ed 1st Ed (1992) (1938)

Robert B Layzer MD (1931-present) b Cleveland College- Harvard, studied French, history, literature, and acted in Harvard Theater Group. Won Garrison poetry prize Med School: Harvard Columbia Neuro residency Was a fellow of Lewis Rowland, neuromuscular disease Faculty Columbia 1967 moved to UCSF Neurology dept. after Dr. Fishman Neuromuscular faculty there his whole career. Publications on Periodic Paralysis , Muscle Energy Metabolism, Motor Unit Hyperactivity State Book: Neuromuscular Manifestation of System Disease (1985)