Invest. Ophthalmol. Vis. Sci ;56(1): doi: /iovs Figure Legend:

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From: Correlation Between Light Levels and the Development of Deprivation Myopia Invest. Ophthalmol. Vis. Sci.. 2015;56(1):299-309. doi:10.1167/iovs.14-15499 Figure Legend: Histology of retinal tissue from bright light–treated chicks. (A, B) Retinal sections stained with H&E from bright light (40,000 lux [A])– and normal light (500 lux [B])–treated chicks. No differences in general retinal histology were detectable between the two light treatments. (C–F) TUNEL-labeled sections, costained with DAPI. (C) Incubation with secondary antibody alone (negative control) did not show specific cell labeling, with only weak autofluorescence observed. (D) Positive TUNEL control tissue. DNA damage and apoptosis was observed in photoreceptor cell bodies located in the outer nuclear layer of the SD rat retina following light damage induced by exposure to 1500 lux for a period of 24 hours. This tissue was processed in parallel with retinal tissue obtained from the chicken. (E, F) Retinal sections from bright light (E)– and normal light (F)–treated birds. Neither lighting condition showed TUNEL labeling. Date of download: 10/20/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.