Aim: How does HIV affect the immune system?

What could have made him look so sick?

Passed through the placenta Open wound Sharing needles - drugs How can we contract HIV? Sexual intercourse Blood transfusion Passed through the placenta Open wound Sharing needles - drugs Do phenolthalein activity

It is a virus that attacks our immune system. What is HIV? It is a virus that attacks our immune system. It is a retrovirus. It has RNA not DNA as its genetic material. How does our body know this is an enemy? ANTIGEN

What part of our immune system does it attack? White blood cells HIV attacks special WBC’s called T-Cells

How are B-cells different than T-cells? Send signals to B-cells to make antibodies Make antibodies

How does HIV replicate? HIV binds to a T-cell Virus HIV binds to a T-cell It inserts its RNA into the T-cell It produces HIV DNA It hides HIV DNA inside the cell's DNA: This turns the cell into a HIV factory. T-Cell

How does HIV destroy our immune system? Time 1:43

Effects of HIV You don’t die from the HIV infection, rather you die from the diseases/infections you get because your body can’t defend itself. (ex: pneumonia) These infections are called OPPORTUNISTIC INFECTIONS.

Can we make a vaccine? 3 min clip It is very difficult because the virus mutates very quickly and produces different antigens after only a few generations.

Where is AIDS an epidemic?