Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk Mignon T. van den Elzen, MD, Harmieke.

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Presentation transcript:

Allergenicity and safety of recombinant human C1 esterase inhibitor in patients with allergy to rabbit or cow's milk Mignon T. van den Elzen, MD, Harmieke van Os-Medendorp, PhD, Heike Röckmann-Helmbach, MD, PhD, Els van Hoffen, PhD, Ans F.M. Lebens, BSc, Helma van Doorn, BAS, Rob J.B. Klemans, MD, PhD, Carla A.F.M. Bruijnzeel-Koomen, MD, PhD, C. Erik Hack, PhD, Leonard Kaufman, PhD, Anurag Relan, MD, André C. Knulst, MD, PhD Journal of Allergy and Clinical Immunology Volume 138, Issue 2, Pages 476-481.e1 (August 2016) DOI: 10.1016/j.jaci.2016.04.019 Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Flowchart of inclusion and exclusion of patients. Journal of Allergy and Clinical Immunology 2016 138, 476-481.e1DOI: (10.1016/j.jaci.2016.04.019) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 BAT results. Rabbit extract consists of rabbit dander proteins, whereas rabbit WAP consists of rabbit whey proteins and therefore represents rabbit milk. BAT results are positive for each patient when the percentage of CD63-positive cells exceeds 5% (dotted line). WAP, Whey acidic protein. Journal of Allergy and Clinical Immunology 2016 138, 476-481.e1DOI: (10.1016/j.jaci.2016.04.019) Copyright © 2016 American Academy of Allergy, Asthma & Immunology Terms and Conditions