Translating regenerative medicine to the clinic

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Presentation transcript:

Translating regenerative medicine to the clinic Alicia El Haj Director ISTM / Chair in Regenerative Medicine

Stem Cell therapy at Keele Professor James Richardson Orthopaedic Trials Cartilage - ACI chondrocytes – MRC - ACTIVE TRIAL chondrocytes/MSC- ARUK/MRC ASCOT TRIA Non Unions fractures BM Mesenchymal stem cells (MSC) Stroke Trials Athersys – MSC IV Lab built with charity money 2 GMP cell therapy laboratory >500 patients with ACT founded 2000 Royal Stoke Hospital Oswestry RJAH Orthopaedic Hospital 2

Establishing the Cell Therapy Pipeline Bioreactor growth environments Delivery systems and scaffolds Targeting, activation and tracking

Arthritis Research UK Centre for Tissue Engineering Medical Research Council UKRMP Hub in Stem cell niche MRC UKRMP Hub in Acellular Delivery Engineering and Physical Sciences Research Council Centre for Innovative Manufacturing in Regenerative Medicine Biotechnology and Bioscience Research Council LOLA scheme Nottingham, Loughborough, Liverpool, Edinburgh, Imperial, Kings, Manchester. Southampton, York, Cambridge, Aberdeen, Newcastle, UCL

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