Biomaterials: Stem Cell Differentiation

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Presentation transcript:

Biomaterials: Stem Cell Differentiation Ronald Richardson II Be 2352 Section2

Overview What are biomaterials? Types of biomaterials? Specific target of processing biomaterials Advancements in biomaterial technology Conclusion

Biomaterials Materials that can be either synthetic or natural, that are used for medical devices that come in contact with biological systems Terms For Later: Stem cells Scaffolds

Types of Biomaterials Synthetic Natural Polymer Peptide Proteins Collagen, fibrin, and silk Polysaccharides Agarose, alginate, hyaluronan, chitosan

Synthetic Biomaterials Polymer PLGA (polylactic-co-glycolic acid) PEG (polyethylene glycol) Peptide Form Hydroxyapatite

Natural Biomaterials Protein based Polysaccharide based Collagen Fibrin Silk Polysaccharide based Agarose Alginate Hyaluronan chitosan

Equation for Photochemical Modification CD- Minimum feature size K1- coefficient for factors in the process - lambda NA- numerical aperture

Advancements Biomaterial use is growing and improving Drawbacks Advantages

Conclusion Effectiveness in Biomaterials Benefits are proven to be fairly long term

Questions?

Work Cited Bettina Hohlweg-Majert, Dr. Rainer Schmelzeisen, Dr. Nassrin Kiapur. Different growing of osteoblasts on 3D structures in comparison with industrial and individual materials. 9 June 2003. 27 November 2011 <http://ipj.quintessenz.de/index.php?doc=html&abstractID=21009>. Freeform Fabrication of Photocured PEG Scaffolds for Tissue Engineering. October 2009. 27 November 2011 <http://www.biomaterials.org/week/bio36.cfm>. Geltser, Ilia. Tissue Engineering Scaffold Fabrication. 14 April 2004. 27 November 2011 <http://www- bioc.rice.edu/bios576/scaffolds/Scaffolds.htm>. Glycosan Biosystems. Natural vs Synthetic Biomaterials. n.d. 27 November 2011 <http://www.glycosan.com/ha_science/natural_vs_synthetic_biomaterials.html>. Materials Science and Chemical Engineering Department Politecnico di Torino. Biomaterials. n.d. 27 November 2011 <http://www.composites.polito.it/bio.html>. Ratner, Buddy. Biomaterials Tutorial. 2004. 27 November 2011 <http://www.uweb.engr.washington.edu/research/tutorials/introbiomat.html>. Stem Cell Information. 24 March 2009. 27 November 2011 <http://stemcells.nih.gov/info/scireport/chapter1.asp>. Surface modification of biomaterials with proteins. n.d. 27 November 2011 <http://en.wikipedia.org/wiki/Surface_modification_of_biomaterials_with_proteins>. Willerth, Shelly Elbert. Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery. 2008. 27 November 2011 <http://www.stembook.org/node/450#F1>.