Diagnostic and Immunosuppressive Potential of Elevated Mir-424 Levels in Circulating Immune Cells of Ischemic Stroke Patients Li Guangwen 1, 2 ;Ma Qingfeng.

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Diagnostic and Immunosuppressive Potential of Elevated Mir-424 Levels in Circulating Immune Cells of Ischemic Stroke Patients Li Guangwen 1, 2 ;Ma Qingfeng 1 ;Wang Rongliang 1, 2 ;Fan Zhibin 1, 2 ;Tao Zhen 1, 2 ;Liu Ping 1 ;Zhao Haiping 1, 2 ;Luo Yumin 1, 2, 3 ; 1 Cerebrovascular Diseases Research Institute and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China ; 2 Beijing Geriatric Medical Research Center and Beijing Key Laboratory of Translational Medicine for Cerebrovascular Diseases, Beijing, China ; 3 Beijing Institute for Brain Disorders, Beijing, China ; Figure 5. Correlations between changes in plasma TNF-#cod#x003B1; and IL-10 levels with miR-424 levels in lymphocytes and neutrophils. A TNF-#cod#x003B1; levels in plasma from 33 stroke patients and 24 control volunteers; #cod#x0002A;#cod#x0002A;#cod#x0002A; p #cod#x0003C;0.001 compared to control. B Correlation between miR-424 levels in lymphocyte and TNF-#cod#x003B1; levels in plasma from 33 AIS patients. C Correlation between miR-424 levels in neutrophils and TNF-#cod#x003B1; levels in plasma from 33 AIS patients; D IL-10 levels in plasma from 33 stroke patients and 24 control volunteers. E Correlation between miR-424 levels in lymphocytes and IL-10 levels in plasma from 33 AIS patients; F Correlation between miR-424 levels in neutrophils and IL-10 levels in plasma from 33 AIS patients. Data represent mean#cod#x000B1;SEM. TNF-#cod#x003B1;, tumor necrosis factor-alpha; IL-10, interleukin-10. AIS, acute ischemic stroke. null,null,0(0),null-null. Doi:10.14336/AD.2017.0602