Chapter 71: Vitamin D– Related Disorders Paul Lips, Natasja M. van Schoor, and Nathalie Bravenboer

Table 1. Classification of Vitamin D–Deficient Status From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Table 1. Classification of Vitamin D–Deficient Status © 2008 American Society for Bone and Mineral Research

Table 2. Causes of Rickets and Osteomalacia From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Table 2. Causes of Rickets and Osteomalacia © 2008 American Society for Bone and Mineral Research

From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Table 3. Recommended Dietary Intake of Vitamin D in Micrograms per Day* © 2008 American Society for Bone and Mineral Research

From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Figure 1 Figure 1 The pathway from vitamin D deficiency to falls and fractures. Figure 1 The pathway from vitamin D deficiency to falls and fractures. © 2008 American Society for Bone and Mineral Research

From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Figure 2 Figure 2 Osteomalacia in a patient with celiac disease. Goldner stain: mineralized bone is black and osteoid tissue is gray. Besides thick osteoid seams, increased bone resorption by multinucleated osteoclasts (arrows) is visible. Figure 2 Osteomalacia in a patient with celiac disease. Goldner stain: mineralized bone is black and osteoid tissue is gray. Besides thick osteoid seams, increased bone resorption by multinucleated osteoclasts (arrows) is visible. © 2008 American Society for Bone and Mineral Research

From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Figure 3 Figure 3 Rickets in a child 1.5 yr of age. (Top) Florid rickets with typical unsharp concave margin of the ulna (arrow). (Bottom) Healing of rickets and appearance of new ossification centers (arrowheads). Figure 3 Rickets in a child 1.5 yr of age. (Top) Florid rickets with typical unsharp concave margin of the ulna (arrow). (Bottom) Healing of rickets and appearance of new ossification centers (arrowheads). © 2008 American Society for Bone and Mineral Research

From the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism, 7th Edition. www.asbmrprimer.org Figure 4 Figure 4 Pseudofracture (arrow) in the left os ilium in a patient with osteomalacia. Figure 4 Pseudofracture (arrow) in the left os ilium in a patient with osteomalacia. © 2008 American Society for Bone and Mineral Research