Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: Sagittal magnetic resonance images of representative healthy (Grade I, left) and degenerated (Grade III, right) intervertebral disks

Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: (Top) Schematic of the specimen dissection orientations for the uniaxial (radial) and biaxial (axial-circumferential) tension experiments. (Middle) Representative samples tested under biaxial (left) and uniaxial (right) tension. (Bottom) Diagonal cross-section of a representative specimen under the microscope (bottom-left), the associated gray-scale image (bottom-middle), and the isolated view used for thickness quantification (bottom-right).

Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: Experimental measurements and model predictions for two representative samples under uniaxial loading in the radial direction

Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: Model predictions and experimental stress measurements for a particular healthy sample in 1:0, 0:1, 1:1, and 2:1 (axial:circumferential) loading conditions

Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: Model predictions and experimental stress measurements for a particular degenerated sample in 1:0, 0:1, 1:1, and 2:1 (axial:circumferential) loading conditions

Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: Fiber and matrix contributions to the total SED generated under the four tested biaxial loading configurations. Model predictions for both healthy and degenerated conditions are based on the mean optimized coefficients. All values are reported in KPa.

Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: The range of motion predictions under pure-moment loading for all modeled scenarios: (top) extension (– moment) and flexion (+ moment); (bottom, left) unilateral lateral bending; and (bottom, right) uniaxial rotation

Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: Nodal intradiskal von Mises stress predictions (middle row) and strain energy density percentage due to the matrix component (bottom row) in the annulus in the anteroposterior direction under extension (left) and flexion (middle) and in the medial-lateral direction under lateral bending (right). The white arrows indicate the positions of the nodes in the annulus corresponding to the horizontal axes of the charts below.

Date of download: 10/22/2017 Copyright © ASME. All rights reserved. From: Modeling Degenerative Disk Disease in the Lumbar Spine: A Combined Experimental, Constitutive, and Computational Approach J Biomech Eng. 2012;134(10):101003-101003-11. doi:10.1115/1.4007632 Figure Legend: The percentage contribution of the matrix component to the average SED predictions in the annulus fibrosus