Fig. 3. HNF1β and ERβ expressions in O-CCC. (A and B) HNF1β expression

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Fig. 3. HNF1β and ERβ expressions in O-CCC. (A and B) HNF1β expression Fig. 3. HNF1β and ERβ expressions in O-CCC. (A and B) HNF1β expression. (A) Complete loss of HNF1-β is rarely found in CCC. However, negative expression of p53 or ER with loss of ARID1A is common (DAB, ×100). (B) Luminal hobnail cells express HNF1-β. More HNF1-β expression occurs in cells closer to the luminal side (DAB, ×200). (C and D) ERβ expression. (C) complete loss of ERβ is common (DAB, ×100). (D) Luminal protruding hobnail cells express ERβ (DAB, ×100). ERβ, estrogen receptor beta; O-CCC, clear cell carcinoma of ovary; ARID1A, AT-rich DNA-interacting domain 1A; DAB, 3'-3' diaminobenzidine. Fig. 3. HNF1β and ERβ expressions in O-CCC. (A and B) HNF1β expression. (A) Complete loss of HNF1-β is rarely found in CCC. However, negative expression of p53 or ER with loss of ARID1A is common (DAB, ×100). (B) Luminal hobnail cells express HNF1-β. More HNF1-β expression occurs in cells closer to the luminal side (DAB, ×200). (C and D) ERβ expression. . . Yonsei Med J. 2017 Jan;58(1):59-66. https://doi.org/10.3349/ymj.2017.58.1.59