Volume 71, Issue 6, Pages (June 2017)

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Volume 71, Issue 6, Pages 896-903 (June 2017) Why and Where do We Miss Significant Prostate Cancer with Multi-parametric Magnetic Resonance Imaging followed by Magnetic Resonance-guided and Transrectal Ultrasound-guided Biopsy in Biopsy-naïve Men? Martijn G. Schouten, Marloes van der Leest, Morgan Pokorny, Martijn Hoogenboom, Jelle O. Barentsz, Les C. Thompson, Jurgen J. Fütterer European Urology Volume 71, Issue 6, Pages 896-903 (June 2017) DOI: 10.1016/j.eururo.2016.12.006 Copyright © 2016 European Association of Urology Terms and Conditions

Fig. 1 Flowchart describing the diagnostic pathways. All patients underwent both multi-parametric magnetic resonance imaging (MRI) and transrectal ultrasound (TRUS)-guided biopsy. Patients with a Prostate Imaging Reporting and Data System (PI-RADS) ≥3 on multi-parametric MRI received MR image-guided biopsy in addition to TRUS biopsy. European Urology 2017 71, 896-903DOI: (10.1016/j.eururo.2016.12.006) Copyright © 2016 European Association of Urology Terms and Conditions

Fig. 2 Distribution maps of cancer positive segments in patients with significant prostate cancer on magnetic resonance image-guided biopsy (MR-Bx; left) and transrectal ultrasound-guided biopsy (TRUS-Bx; right). The anterior portion of the prostate was defined by a hypothetical line drawn 17mm anterior from the posterior prostatic surface irrespective of prostate size, which represents the core length commonly used during TRUS-Bx [17]. SV=seminal vesicles. European Urology 2017 71, 896-903DOI: (10.1016/j.eururo.2016.12.006) Copyright © 2016 European Association of Urology Terms and Conditions

Fig. 3 Distribution maps of the segments of significant prostate cancer lesions that were missed with magnetic resonance image-guided biopsy (MR-Bx; left) and transrectal ultrasound-guided biopsy (TRUS-Bx; right). SV=seminal vesicles. European Urology 2017 71, 896-903DOI: (10.1016/j.eururo.2016.12.006) Copyright © 2016 European Association of Urology Terms and Conditions