INCREASED CSF LEVELS OF BIOMARKERS FOR NEURODEGENERATION IN FTLD-GRN MUTATION CARRIERS  Joery Goossens, Sara Van Mossevelde, Tobi Van den Bossche, Anne.

Slides:



Advertisements
Similar presentations
Linkage and Association Studies Identify a Novel Locus for Alzheimer Disease at 7q36 in a Dutch Population-Based Sample Rosa Rademakers, Marc Cruts, Kristel.
Advertisements

Functional Analysis of the Neurofibromatosis Type 2 Protein by Means of Disease- Causing Point Mutations Renee P. Stokowski, David R. Cox The American.
2015 Alzheimer's disease facts and figures Alzheimer's & Dementia: The Journal of the Alzheimer's Association Volume 11, Issue 3, Pages (March.
Sleep disruption changes across the disease trajectory: Pilot findings from the healthy patterns sleep study Nancy A. Hodgson, Albert J. Safi Alzheimer's.
Capillary dysfunction in Alzheimer's disease
Investigating the role of ALS genes CHCHD10 and TUBA4A in Belgian FTD-ALS spectrum patients  Federica Perrone, Hung Phuoc Nguyen, Sara Van Mossevelde,
DIAGNOSTIC ACCURACY AND CONFIDENCE IN THE CLINICAL DETECTION OF COGNITIVE IMPAIRMENT IN EARLY-STAGE PARKINSON’S DISEASE  Kathryn A. Wyman-Chick, Phillip.
Vladimir S. Fonov, Mahsa Dadar, Xiao Yiming, D. Louis Collins 
Are early atrophy patterns in autosomal dominant familial Alzheimer's disease gene- dependent?  Kirsi Kinnunen, Natalie Ryan, David Cash, António Bastos.
Relationship between Microstructural Degeneration of the Corpus Callosum, White Matter Hyperintensities, and Motor Function in Cognitively Intact Elderly 
Hilkka Liedes, Jyrki Lötjönen, Gerald P. Novak, Mark Forrest Gordon 
A SYSTEMATIC REVIEW AND META-ANALYSIS COMPARING QUALITY-OF-LIFE RATINGS FROM FAMILY AND PAID CAREGIVERS OF PEOPLE WITH DEMENTIA RESIDING IN CARE HOMES 
Mutation frequency of pathogenic genes in familial Alzheimer’s disease in China  Jianping Jia, Liyong Wu, Wei Qin, Dan Li, Luxi Shen, Hanzhi Li, Qianqian.
Cerebrospinal fluid biomarkers for Alzheimer's disease are associated with neuropathology in cortical brain biopsy  Toni Seppälä, Ossi Nerg, Anne Koivisto,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Interaction network of tau protein, beta-amyloid protein, and amyloid protein precursor under oxidative stress in Alzheimer’s disease  Eduardo de Souza/S.
SERUM NEUROFILAMENT LIGHT PROTEIN PREDICTS CLINICAL OUTCOME IN TRAUMATIC BRAIN INJURY  Pashtun Shahim, Magnus Gren, Victor Liman, Ulf Andreasson, Niklas.
The differential diagnosis of amnestic mild cognitive impairment and Alzheimer's disease dementia by hippocampal volume measurement with MR in a chinese.
Localization of Hippocampal atrophy in Alzheimer's disease
Cerebrospinal fluid Aβ42 is the best predictor of clinical progression in patients with subjective complaints  Argonde C. van Harten, Pieter Jelle Visser,
A NOVEL NEUROIMAGING APPROACH TO CAPTURE COGNITIVE RESERVE
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Christine Bredfeldt, Kristen Rice, Lisa Alecxih 
SMARTPHONE TECHNOLOGY TO MEASURE HEALTH CHARACTERISTICS IN OFFSPRING OF PATIENTS WITH DEMENTIA: THE IVITALITY PROOF-OF- PRINCIPLE STUDY  Liselotte Wijsman,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
KETOGENIC DIET EFFECTS ON BRAIN KETONE METABOLISM AND ALZHEIMER'S DISEASE CSF BIOMARKERS  Suzanne Craft, Bryan J. Neth, Akiva Mintz, Kiran Sai, Nora Shively,
The effect of using a conditional discrimination procedure to teach name-face relation to a person diagnosed with dementia  Hanna S. Steingrimsdottir,
Application of Resource Utilization in Dementia (RUD) instrument in a global setting  Anders Wimo, Anders Gustavsson, Linus Jönsson, Bengt Winblad, Ming-Ann.
Alzheimer’s disease core biomarkers and prediction of dementia in MCI: The effect of age at onset  Anna Caroli, Samantha Galluzzi, Clarissa Ferrari, Annapaola.
LATENT-FACTOR STRUCTURE OF THE DELCODE STUDY NEUROPSYCHOLOGICAL TEST BATTERY  Steffen Wolfsgruber, Luca Kleineidam, Jannis Guski, Oliver Peters, Katharina.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
The global prevalence of dementia: A systematic review and metaanalysis  Martin Prince, Renata Bryce, Emiliano Albanese, Anders Wimo, Wagner Ribeiro, Cleusa.
HYPERGLYCEMIA: PREDISPOSITION FOR MICROEMBOLI, STROKE, AND WHITE MATTER CHANGES  Leila Parand, Saif Bushnaq, Yue Wang, Lenora Mathes, Dinesh Jillella,
DETECTING COGNITIVE DISORDERS USING THE MUISTIKKO WEB-BASED COGNITIVE TEST BATTERY: VALIDATION IN THREE COHORTS  Teemu Paajanen, Shadi Mahdiani, Marie.
Marjolein Bulk, Linda van der Graaf, Walid M
Colin Groot, Chris W. J. van der Weijden, Wiesje M
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Japanese brain bank network for neuroscience research
BIOLOGICAL PATHWAYS FOUND IN COMMON BETWEEN ALZHEIMER’S DISEASE AND MAJOR DEPRESSION: A STUDY ON MICRORNA EXPRESSION IN A SYSTEMATIC REVIEW  Ana Paula.
A TRANSCULTURAL COGNITIVE MARKER OF ALZHEIMER'S DISEASE
Community environment and incident dementia: Results from the three-city study  Claudine Berr, Laure Anne Gutierrez, Sylvaine Artero, Catherine Helmer,
Ara S. Khachaturian, David P
Effect of hypertension and antihypertensive medication on executive function, brain atrophy, and white matter hyperintensities  Shannon L. Risacher, Li.
Application of Resource Utilization in Dementia (RUD) instrument in a global setting  Anders Wimo, Anders Gustavsson, Linus Jönsson, Bengt Winblad, Ming-Ann.
Deconstructing language disintegration: Primary progressive aphasias have specific tractographic signatures  Colin Mahoney, Ian Malone, Ged Ridgway, Aisling.
LIFESPAN OF ONE FOCUSED ULTRASOUND MEDIATED BLOOD-BRAIN BARRIER TREATMENT IN A MOUSE MODEL OF ALZHEIMER'S DISEASE  Charissa Poon, Kullervo Hynynen  Alzheimer's.
A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ42  Kristel Sleegers,
Shruti Mishra, Brian Andrew Gordon, Karl A
Comparison of visual and quantitative florbetapir-PET reads in subjects with early Alzheimer's disease for assessing amyloid burden  Bradley Wyman, Yahong.
The incremental diagnostic value of 18F-florbetapir imaging in naturalistic patients with cognitive impairment: The India-FBP study  Marina Boccardi,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Added value of 11C-PiB-PET imaging in the diagnosis of Alzheimer's disease  Kristian Frederiksen, Anne-Mette Hejl, Ian Law, Steen Hasselbalch, Gunhild.
Mark D. Meadowcroft, Douglas G. Peters, Carson J
Amygdalar local structural differences in early- and late-onset Alzheimer's patients  Enrica Cavedo, Michela Pievani, Marina Boccardi, Samantha Galluzzi,
COGNITIVE COMPLAINTS IN OLDER ADULTS AT RISK FOR ALZHEIMER’S DISEASE ARE ASSOCIATED WITH ALTERED RESTING STATE NETWORKS  Joey A. Contreras, Joaquín Goñi,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
MR-less cortical surface-projection of PET images from 11C- and 18F-labeled radiotracers  Vincent Doré, Pierrick Bourgeat, Luping Zhou, Jurgen Fripp,
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
GREY MATTER CONNECTIVITY IS ASSOCIATED WITH CLINICAL PROGRESSION IN NON-DEMENTED, AMYLOID POSITIVE PATIENTS  Betty M. Tijms, Mara ten Kate, Sander C.J.
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
Alzheimer's Association towards Guidelines for Dementia Care Practice: Recommendations with emphasis on high-quality, person-centered care in long-term.
Brain amyloid deposition and metabolism in early and late mild cognitive impairment  Jared Rowley, Liyong Wu, Sara Mohades, Marina Dauar, Antoine Leuzy,
Tharick A. Pascoal, Sulantha S
The Gene Encoding Nicastrin, a Major γ-Secretase Component, Modifies Risk for Familial Early-Onset Alzheimer Disease in a Dutch Population-Based Sample 
Alzheimer's & Dementia: The Journal of the Alzheimer's Association
INTRINSIC CONNECTIVITY NETWORKS IN POSTERIOR CORTICAL ATROPHY: A ROLE FOR THE PULVINAR?  Carolyn A. Fredericks, Jesse Brown, Jersey Deng, Rik Ossenkoppele,
Automated detection of beta-amyloid–related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI 
Extracting white matter hyperintensities in Alzheimer's disease risk and aging studies using supervised segmentation methods  Vamsi Ithapu, Vikas Singh,
BRAIN AMYLOIDOSIS AND COGNITIVE DECLINE IN MCI: 12-MONTH FOLLOW-UP
Michael Navitsky, Abhinay D. Joshi, Michael D. Devous, Michael J
Presentation transcript:

INCREASED CSF LEVELS OF BIOMARKERS FOR NEURODEGENERATION IN FTLD-GRN MUTATION CARRIERS  Joery Goossens, Sara Van Mossevelde, Tobi Van den Bossche, Anne Sieben, Jean-Jacques Martin, Johan Goeman, Peter Paul de Deyn, Christine Van Broeckhoven, Julie van der Zee, Sebastiaan Engelborghs  Alzheimer's & Dementia: The Journal of the Alzheimer's Association  Volume 12, Issue 7, Pages P1058-P1059 (July 2016) DOI: 10.1016/j.jalz.2016.06.2211 Copyright © 2016 Terms and Conditions

Figure 1 Cox hazard regression analysis of disease duration in GRN carriers (n=59) versus C9orf72 carriers (n=53) with pure dementia (p=0.051), corrected for age at onset. Numbers include deceased patients (GRN: n=40; C9orf72: n=30) and living patients censored at time of last evaluation (GRN: n=19; C9orf72: n=23). Alzheimer's & Dementia: The Journal of the Alzheimer's Association 2016 12, P1058-P1059DOI: (10.1016/j.jalz.2016.06.2211) Copyright © 2016 Terms and Conditions

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.