Figure 1. (A) Assay for sLOX-1 in plasma from patients with pre-eclampsia (PE) and matched normal pregnant (NP) controls (n = 6). (B) Assay for oxLDL in plasma from patients with PE and matched NP controls (n = 6). From: Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein-1 Receptor Protects Against Plasma-Mediated Vascular Dysfunction Associated With Pre-Eclampsia Am J Hypertens. 2013;26(2):279-286. doi:10.1093/ajh/hps035 Am J Hypertens | © American Journal of Hypertension, Ltd 2012. All rights reserved. For Permissions, please email: journals.permissions@oup.com
Figure 2. (A) Effect of bradykinin (BK) on vasorelaxation after overnight incubation of omental vessels from normal pregnant (NP) women in plasma from normal pregnant (NP) women and plasma from women with pre-eclampsia (PE) with or without 30 minutes of administration of IgG (n = 6) #P < 0.001 vs. NP plasma. *P < 0.001 vs. NP plasma. (B) Effect of 30 minutes of treatment with oxLDL and administration of TS20 on the relaxation responses to bradykinin (BK) of omental vessels from NP women incubated with NP and PE plasma (n = 6) #P < 0.001 vs. PE plasma oxLDL. *P < 0.001 vs. PE Plasma. From: Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein-1 Receptor Protects Against Plasma-Mediated Vascular Dysfunction Associated With Pre-Eclampsia Am J Hypertens. 2013;26(2):279-286. doi:10.1093/ajh/hps035 Am J Hypertens | © American Journal of Hypertension, Ltd 2012. All rights reserved. For Permissions, please email: journals.permissions@oup.com
Figure 3. (A) Effect of sodium nitroprusside (SNP) on the relaxation responses of omental vessels from normal pregnant (NP) women after overnight incubation of the vessels in normal pregnant (NP) and pre-eclampsia (PE) plasma and 30 minutes of administration of IgG (n = 6). (B) Effect of SNP on the relaxation responses of omental vessels from NP women incubated in NP or PE plasma with 30 minutes of administration of oxidized low-density lipoprotein (oxLDL) with or without the anti-LOX-1 antibody (TS20) (n = 6). From: Inhibition of Lectin-Like Oxidized Low-Density Lipoprotein-1 Receptor Protects Against Plasma-Mediated Vascular Dysfunction Associated With Pre-Eclampsia Am J Hypertens. 2013;26(2):279-286. doi:10.1093/ajh/hps035 Am J Hypertens | © American Journal of Hypertension, Ltd 2012. All rights reserved. For Permissions, please email: journals.permissions@oup.com