Volume 119, Issue 4, Pages 1027-1033 (April 2001) The Utility of Peak Flow, Symptom Scores, and β-Agonist Use as Outcome Measures in Asthma Clinical Research  Leone Frank T. , MD, MS, Mauger Elizabeth A. , PhD, Peters Stephen P. , PhD, MD, FCCP, Chinchilli Vernon M. , PhD, Fish James E. , MD, FCCP, Boushey Homer A. , MD, Cherniack Reuben M. , MD, Drazen Jeffrey M. , MD, FCCP, Fahy John V. , MD, Ford Jean , MD, FCCP, Israel Elliot , MD, FCCP, Lazarus Stephen C. , MD, Lemanske Robert F. , MD, Martin Richard J. , MD, McGeady Stephen J. , MD, Sorkness Christine , PharmD, Szefler Stanley J. , MD  CHEST  Volume 119, Issue 4, Pages 1027-1033 (April 2001) DOI: 10.1378/chest.119.4.1027 Copyright © 2001 The American College of Chest Physicians Terms and Conditions

Figure 1 Representative ROC curves of several surrogate markers of disease severity. The diagonal line represents the ROC curve of a test with no discriminative capacity (ie, random results), while a theoretical test with perfect discriminative capacity would have a ROC curve that follows the left-uppermost boundaries of the plot (heavy lines). CHEST 2001 119, 1027-1033DOI: (10.1378/chest.119.4.1027) Copyright © 2001 The American College of Chest Physicians Terms and Conditions