AN EFFECTIVE AND SLIMMING ACTIVE INGREDIENT LIPOREDUX AN EFFECTIVE AND SLIMMING ACTIVE INGREDIENT

A Picture… LIPOREDUX

SKIN The more extended body organ LIPOREDUX DISTINCT ACTION LEVELS Moisturisers Emollients Stratum Corneum Epidermis Lighteners Anti cellulitis Dermis Anti stretch-marks Body Tissue

CLA Coniugated Linoleic Acid (Blend of isomers) LIPOREDUX CLA Coniugated Linoleic Acid (Blend of isomers) L-Carnitine Aminoacid (Endogenous Transporter) LIPOREDUX o COO- N+ CH3

L-CARNITINE Discovered in 1905 in muscular tissues. LIPOREDUX Discovered in 1905 in muscular tissues. Transports long chains of fatty acids from cytosol to the mitochondrions. There, the process continues with β oxidation  Krebs cycle  oxidative phosphorylation  …  the production of energy in the ATP form. THIS MEANS… Lipolitic activity!

ConiugatedLinoleicAcid LIPOREDUX an essential fat Blend of isometric forms of linoleic acid (which means structural variants) is the mixture of isomers derived from linoleic acid (that represents the double bonds at the level of carbon atoms 9 and 11 or 10 and 12) with all the possible cis- and trans- combinations.

CLA’s PROPERTIES LIPOREDUX Promotes the reduction of body fat and helps thin mass development in 90 days a 20 % decrease in body fat without significant weight shift (from a recent research) Promotes the Strengthening of the lean mass (Research programme at Wisconsin University on subjects who were given CLA) Reduces the dimension of adipocytes, but does not affect their number (In a recent study conducted with the purpose of assessing CLA’s action dynamic in relation to the lipidic metabolism.)

LIPOREDUX LIPOREDUX Expected SYNERGISTIC biological action in comparison to individual molecules

Expected SYNERGISTIC biological action (in comparison to individual molecules) LIPOREDUX Sensible reduction of the body fat Lean body mass development Increased metabolic efficiency better use of the high energy molecules (lipids) leads to more fat burning during exercise

Immediate availability More Carnitine concentration at deep cell level ADVANTAGES LIPOREDUX Immediate availability More Carnitine concentration at deep cell level

LIPOREDUX IN-VITRO TEST

LIPOLYTIC EFFECT ON ADIPOCYTES (in-vitro) LIPOREDUX Adipocytes isolated with collagenasis from epidermis and adipose tissue (Detection of the) amount of glycerine released at increasing Liporedux concentrations (as µmole of glycerin on 100 mg of lipid)

RESULTS LIPOREDUX / / / /

LIPOREDUX IN-VIVO TEST

IN-USE TEST Half body test - Subjective evaluation LIPOREDUX Half body test - Subjective evaluation 15 female subjects (25 – 45 years) Emulsion containing 4% of LIPOREDUX Vs. Placebo emulsion (direct comparison) Two applications per day, for 4 weeks

RESULTS Enhancement Worsening EMOLLIENCY - SMOOTHNESS - ELASTICITY % LIPOREDUX Enhancement Worsening % EMOLLIENCY - SMOOTHNESS - ELASTICITY

RESULTS LIPOREDUX Reduction Increase % ORANGE PEEL SKIN

SILHOUETTE APPEARANCE RESULTS LIPOREDUX SILHOUETTE APPEARANCE Enhancement Worsening %

COMPRESSION PAIN (pinching) RESULTS LIPOREDUX COMPRESSION PAIN (pinching) % Reduction Increase

RESULTS LIPOREDUX SKIN TEXTURE Enhancement Worsening %

AFTER 4 WEEKS OF TREATMENT Enhancement / Increase SUMMARY OF RESULTS LIPOREDUX AFTER 4 WEEKS OF TREATMENT Enhancement / Increase Worsening / Reduction %     

AFTER 4 WEEKS OF TREATMENT THIGH CIRCUMFERENCE LIPOREDUX AFTER 4 WEEKS OF TREATMENT FROM A MINIMUM OF – 4 mm (0,157 inch) UP TO A MAXIMUM OF – 12 mm (0,551 inch)

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