RADIOBIOLOGY: PART TWO

Slides:

Advertisements

Similar presentations

Radiation Safety Course: Biological Effects

Advertisements

Modifiers of Cell Survival: Repair

Adult Stem Cells Stem Cells, Bone Marrow and Blood

Types of cellular damage

Tissue Radiation Biology

Biological Effects of Ionizing Radiation

Days 1-5 Menstruation Menstruation occurs and the lining of the uterus, with a small amount of blood, leaves the body. At this time another egg is maturing.

Nuclear Medicine. International Atomic Energy Agency Part 2: Radiation units and dose quantities Topic 1: Exposure and exposure rate.

Cellular Division. Cell Function Every human cell has a specific function in supporting the total body. Some differences are obvious, as in nerve cells,

EARLY NONSTOCHASTIC EFFECTS/LATE STOCHASTIC EFFECTS

1. What function is represented by the ribosomes? A.1 B.2 C.3 D.4 Science Starter

Radiation Biology RADL 70 Kyle Thornton.

1. Units 2. Theories of the effects of ionizing radiation 3. Cellular level effects 4. Tissue level effects 5. Effects on organismic level 5.1 Deterministic.

EARLY NONSTOCHASTIC EFFECTS/LATE STOCHASTIC EFFECTS Sherer Chapter 7 and 8 Reference: Bushong, Chapter 36 and 37.

Health Effects of Radiation. What Radiation Affects Directly or indirectly, radiation affects the DNA in cells DNA controls the cell’s function and ability.

1 RAD PROT PT 2 Radiobiology and Cells WEEK 7 – 9 RT 244 (2006 – 2010) RADIOBIOLOGY Radiation Protection & Biology CD SERIES RADIATION PROTECTION.

Learning Targets I can describe cell specialization and levels of organization. I can identify how levels of organization work together in an organism.

TVAN Technical Training Health Physics (RADCON) Initial Training Program HPT Revision 2 Page 1 of 13 Cell Structures.

1 DA105 RADIOLOGY RADIATION HEALTH AND SAFETY – Radiation Control for Health and Safety Act – Standardized xray equipment; required filtration,

Biological Effects of Ionizing Radiation Effects of Radiation at the Molecular and Cellular Level Phases of Damage in Irradiated Organism Lecture IAEA.

RADIOBIOLOGY: PART TWO. CELLULAR EFFECTS OF IRRADIATION Instant death Reproductive death Apoptosis, programmed cell death(interphase death) Mitotic or.

Rad T 110 State Syllabus for Radiation Protection.

Reading: Chapter 4.  Radiation Biology is the study of the effects of radiation on living tissue.  X-rays are a form of ionizing radiation. When x-rays.

Sanitary-and-hygienic, ecological and social consequences of radiative and nuclear failures. Anti-radiation and social protection of the population which.

Biological Effects of Ionising Radiation

RAD PROT PT 2 Radiobiology and Cells WEEK 7 – 9 RT

Tracers and Effects of Radiation. Medical Applications of Radioactivity Radiotracers- radioactive nuclides that can be introduced into organisms in food.

Objectives Differentiate between somatic (body) cells and gametes. Compare and contrast diploid and haploid.

Seventh lecture. Radiosensitivity & law of Bergonié and Tribondeau It is not clear why lack of differentiation of the cell results in radiosensitivity.

How do organs work together? Organs work together in organ systems to carry out major life functions.

BIOLOGICAL EFFECTS OF RADIATION. WILLIAM CROOKES Image from:

1 Genetics At the cellular level Delving into Cells, Chromosomes, DNA and Genes.

Rad T 110 Sherer Biologic Effects of Radiation Exposure.

Cell Specialization and Differentiation

Levels of organization

2. Metric Practice-Lab Grade 3. Handout on body systems

The Law of Bergonie & Tribondeau

THE HIERARCHY OF STRUCTURE IN ANIMALS

Biological Effect of Ionizing Radiation

Copyright © 2015 by the American Osteopathic Association.

Deterministic effects of radiation –Ch33

RTMR 284 Chapter 30 : Fundamental Principles of Radiobiology

The Human Body.

Genetic Susceptibility

CELL DIFFERENTIATION.

Levels of Organization

Biological Organization

Biological Organization

Types of Cells We have all sorts of different cells in our body!

Cell growth and repair.

Structural Organization of Cells

Levels of Organization

Levels of Organization

Chromosomal deletions.

7.L.3B.1 Develop and use models to explain how the structural organizations within multicellular organisms function to serve the needs of the organism.

Stem Cells and Cellular Differentiation

Molecular and Cellular Radiation Biology

Health Effects of Radiation

Early Radiation Effects on Organ Systems

Cell Biology and Radiation Genetics

Levels of Organization

WEEK 13 VOCABULARY BRAIN CELL NERVE CELL

The student is expected to: 10C analyze the levels of organization in biological systems and relate the levels to each other and to the whole system.

Levels of Organization

KEY CONCEPT The human body has five levels of organization.

Levels of Organization

Key Area 1.1 – Division and Differentiation of Human Cells

Levels of Organization

KNOWLEDGE AREA: Life at Molecular, Cellular and Tissue Level

Presentation transcript:

RADIOBIOLOGY: PART TWO

CELLULAR EFFECTS OF IRRADIATION Instant death Reproductive death Apoptosis, programmed cell death(interphase death) Mitotic or genetic death Mitotic Delay Interference of Function Chromosome Breakage

Survival curves for Mammalian Cells Shoulder indicates an area of cellular repair with Low LET exposures

Cell radiosensisitivy and Law of Bergonie and Tribondeau Blood cells Epithelial tissue Muscle Tissue Nervous Tissue Reproductive cells Blood Cells ??? Find the dose for Whole body hematologic depression What are stem or precursor cells? What dose moderately to severely deplete bone marrow cells? What are the most sensitive stems cells of human tissue?

Blood Cells -MORE QUESTIONS Is death caused from high doses to red blood cells or white blood cells or platelets?Why? What is the lethal dose for humans? What dose level can impact lymphocytes and why is it so low? Why are radiation patients monitored

Epithelial tissue Muscle Tissue Nervous Tissue Radiosensitive Insenstive When are nerve cells most sensitive?

Reproductive cells Mature spermatogonia-sensitive or insensitive? Why? What dose can cause temporary sterility in male? In female? What dose can cause permanent sterility in male? In female? Mature ova sensitive or insensitive? What dose may suppress male sperm population? When are a woman’s ovaries most sensitive?