Rationale and design of the FreezeAF trial: A randomized controlled noninferiority trial comparing isolation of the pulmonary veins with the cryoballoon.

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Presentation transcript:

Rationale and design of the FreezeAF trial: A randomized controlled noninferiority trial comparing isolation of the pulmonary veins with the cryoballoon catheter versus open irrigated radiofrequency ablation in patients with paroxysmal atrial fibrillation Armin Luik, MD, Matthias Merkel, MD, Danielle Hoeren, Tobias Riexinger, MD, Meinhard Kieser, PhD, Claus Schmitt, MD American Heart Journal Volume 159, Issue 4, Pages 555-560.e1 (April 2010) DOI: 10.1016/j.ahj.2010.01.008 Copyright © 2010 Mosby, Inc. Terms and Conditions

Figure 1 Follow-up of the FreezeAF trial. Blanking period: 3 months. Clinical visits include an interview, ECG, and Holter ECG. Earliest date for redo procedure: 6 months after index procedure. MRI (magnetic resonance imaging)/CT scans: 3 months after last ablation procedure. Seven-day Holter ECG: 6 and 12 months after index procedure. American Heart Journal 2010 159, 555-560.e1DOI: (10.1016/j.ahj.2010.01.008) Copyright © 2010 Mosby, Inc. Terms and Conditions