Ch 1-4: Design of Experiments

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Ch 1-4: Design of Experiments Notes #6 Ch 1-4: Design of Experiments

How to collect statistical data? 2 ways Observational studies - By observing and measuring specific traits, without changing the subjects being studied. Ex. Gallup Poll was established in 1935 to collect public opinion by polling and surveying a worldwide population.

2. Experiment -When some treatment is applied and then observations are made to see its effects on the subjects. Ex. Giving caffeine pills to 100 college freshmen during finals weeks, and measuring amount of hours they can go without sleeping while studying.

Types of Observational Studies Cross-sectional study - Data are measured and collected at one point in time, usually a short term study (≤ 1 year study). Ex. E-cigarettes and conventional cigarette use among US adolescents (2014 Cross Sectional Study ) “The study, which tracked the habits of nearly 700 young people over a year, revealed that young nonsmokers who showed no interest in smoking were more likely to take up the habit if they had used electronic cigarettes.” Khan, A., (2015, September 8) E-cigarettes: Teens who vape are more likely to smoke later, study says. Los Angeles Times. Retrieved from http://www.latimes.com 

2. Retrospective (Case-control) Study - Data collected by going back in time via examining records, interviews, etc. Ex. Japanese Internment Camp Experience recapping the lives of survivors who lived through a traumatic experience.

3. Prospective Study (Longitudinal or Cohort Study) - Data gathered from the same subjects repeatedly over a period of time (usually years or decade long studies). Ex. Cell phone use linked to Brain Cancer Swedish Longitudinal Study conducted for 15 to 25 years

1. Cross-sectional study - Data are measured and collected at one point in time, usually a short term study (≤ 1 year study). 2. Retrospective (Case-control) Study - Data collected by going back in time via examining records, interviews, etc. 3. Prospective Study (Longitudinal or Cohort Study) - Data gathered from the same subjects repeatedly over a period of time (usually years or decade long studies).

Quick Check

Designing an Experiment (The Scientific Method: A 6 Step Process) Stating a Problem. Forming a Hypothesis (“If…, then…” statement) Setting Up the Experiment a. Control Group: A sample group that is left untreated or given a placebo, and is used to compare to the experimental sample group. b. Experimental Group: Sample group receiving the treatment. Be aware of the Placebo Effect (subjects who were untreated may report the same effects as the experimental group. It maybe true or imagined).

The Scientific Method Cont’d 4) Setting Up the Variables (3 Types) a) Independent Variable: The single “thing” that is CHANGED and has made the experimental group different from the control group. b) Controlled Variables: Materials/conditions kept constant between the experimental and control group c). Dependent Variable: What you expect to see or measure as a result from the Independent Variable.

The Scientific Method Con’t 5) Recording and Analyzing Data. 6) Drawing a Conclusion.

Quick Check II You have been given pinto beans to plants and your experiment is to see how much water you will need to grow the tallest plant in 2 months. Identify the following: Two Controlled Variables The Independent Variable The Dependent Variable

Quick Check Answers Controlled Variables -Type of seeds (Pinto Bean) -Amount of time for growth (2 months) -Type of soil, location, pots…etc. b)Independent Variable -Amount of Water c) Dependent Variable(s) -Amount of growth

How to Ruin Experimental Results 2 ways 1. Confounding factors/variables - Occurs in an experiment where you cannot distinguish or tell what led to the change in the final results.

2. Failure to collect a representative sampling of the population Ex 2. Failure to collect a representative sampling of the population Ex. 5 teachers voting to have a 3 week Winter Break, do not represent the entire faculty and staff in the AUSD. 2/3 vote is needed to pass a new vacation proposal.

What is wrong with this experiment? Ex. You want to determine whether or not the amount of light would affect the height of a plant. You adjust different amount of light for each plant, and placed each plant in different potting soil. Was a confounding factor introduced in the experiment? ANS: Yes. The different potting soil will directly influence the growth of the plants, so you can’t determine if it’s the light amount or the soil type that is making a difference in the results.

How to avoid experimental problems 1. Control the effects of the variables ex. Blinding or double blind or rigorously controlled design. 2. Conduct multiple trials and/or have large sample sizes 3. Use randomization ex. Let chance group the subjects.