Scintigraphy with J001 Macrophage Targeting Glycolipopeptide

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Presentation transcript:

Scintigraphy with J001 Macrophage Targeting Glycolipopeptide Putrice Diot, M.D., Etienne Lemarié, M.D., Jean Louis Banlieu, M.D., Sophie Pascal, M.D., Loic Vaillant, M.D., Jean Pierre Revillard, M.D., Ph.D., Hans Binz, M.D., Ph.D., Gérard Normier, Ph.D., Alain Le Pape, Ph.D. CHEST Volume 102, Issue 3, Pages 670-676 (September 1992) DOI: 10.1378/chest.102.3.670 Copyright © 1992 The American College of Chest Physicians Terms and Conditions

Figure 1 A (left) Patient 2: Stage 1 sarcoidosis. Anterior J001 scintigraply with regions of interest on bilateral mediastinal regions of uptake and in shoulder area 3 h after inhalation (scintigraphic index: 1.2). B (right). Patient 2: Stage 1 sarcoidosis. Anterior thoracic gallium scan 48 h after injection. There is a bilateral mediastinal fixation and a physiologic gallium uptake in the liver. CHEST 1992 102, 670-676DOI: (10.1378/chest.102.3.670) Copyright © 1992 The American College of Chest Physicians Terms and Conditions

Figure 2 A (left) Patient 17: Stage 3 sarcoidosis. Posterior J001 scintigraphy 3 h after inhalation. Diffuse pulmonary fixation (scintigraphic index: 1.6). B (right). Patient 17: Stage 3 sarcoidosis. Posterior gallium scan 48 h after injection. Diffuse pulmonary fixation and physiologic gallium uptake in the liver. CHEST 1992 102, 670-676DOI: (10.1378/chest.102.3.670) Copyright © 1992 The American College of Chest Physicians Terms and Conditions

Figure 3 J001 indices at 5 h vs 67 gallium indices at 48 h. CHEST 1992 102, 670-676DOI: (10.1378/chest.102.3.670) Copyright © 1992 The American College of Chest Physicians Terms and Conditions

Figure 4 J001 percent lymphocytes indices at 5 h vs BAL lymphocytosis. CHEST 1992 102, 670-676DOI: (10.1378/chest.102.3.670) Copyright © 1992 The American College of Chest Physicians Terms and Conditions