Measurement of levetiracetam drug levels to assist with seizure control and monitoring of drug interactions with other anti-epileptic medications (AEMs) 

Slides:



Advertisements
Similar presentations
Nonconvulsive status epilepticus in patients with brain tumors
Advertisements

Peter L. Fisher, Adam J. Noble  Seizure - European Journal of Epilepsy 
Ian Morrison, Saif S.M. Razvi  Seizure - European Journal of Epilepsy 
The effects of levetiracetam on urinary 15f-2t-isoprostane levels in epileptic patients  Hilmi Ozden, Sibel Canbaz Kabay, Aysun Toker, Mehmet Cengiz Ustüner,
The relative effectiveness of five antiepileptic drugs in treatment of benzodiazepine- resistant convulsive status epilepticus: A meta-analysis of published.
Vagus nerve stimulation in pediatric epileptic syndromes
Adult nonconvulsive status epilepticus in a clinical setting: Semiology, aetiology, treatment and outcome  Kjersti Nesheim Power, Arne Gramstad, Nils.
Perri Carlson, Kathryn Nicholson Perry 
Post-traumatic seizures—A prospective study from a tertiary level trauma center in a developing country  Amit Thapa, Sarat P. Chandra, Sumit Sinha, V.
Antiepileptic drug therapy the story so far
Effects of levetiracetam monotherapy on sperm parameters and sex hormones: Data from newly diagnosed patients with epilepsy  Mustafa Ceylan, Ahmet Yalcin,
Does ghrelin level change after epileptic seizure in rats?
Has disability discrimination legislation changed the legal framework for epilepsy in the United Kingdom?  Philip Lee  Seizure - European Journal of Epilepsy 
Patients with epilepsy are at an increased risk of subsequent stroke: A population-based cohort study  Chen-Shu Chang, Chun-Hui Liao, Che-Chen Lin, Hsien-Yuan.
Elisabeth Halma, Anton J. A. de Louw, Sylvia Klinkenberg, Albert P
Oxcarbazepine administration and the serum levels of homocysteine, vitamin B12 and folate in epileptic patients: A systematic review and meta-analysis 
Presentation of adult mitochondrial epilepsy
Coral M. Stredny, Nicholas S. Abend, Tobias Loddenkemper 
Do epilepsy specialist nurses use a similar history-taking process as consultant neurologists in the differential diagnosis of patients presenting with.
Anshuman Sengupta, Ali Mahmoud, Shwe Z. Tun, Peter Goulding 
Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, Vitamin B12, folic acid and Vitamin B6  Ufuk Sener, Yasar Zorlu, Oguz.
S. Kılınç, C. Campbell  Seizure - European Journal of Epilepsy 
Four types of traditional Chinese medicine inducing epileptic seizures
Lacosamide monotherapy for partial onset seizures
Severity of anxiety and depression are related to a higher perception of adverse effects of antiepileptic drugs  Bety Gómez-Arias, Daniel Crail-Meléndez,
Four types of traditional Chinese medicine inducing epileptic seizures
Seizure - European Journal of Epilepsy
Smoking reduces serum levels of lamotrigine
The experience of adjusting to a diagnosis of non-epileptic attack disorder (NEAD) and the subsequent process of psychological therapy  Caroline Wyatt,
CSF and plasma adipokines after tonic–clonic seizures
Levetiracetam in the treatment of neonatal seizures: A pilot study
Seizure freedom with VNS monotherapy: A case report
Depression and anxiety in childhood epilepsy: A review
What patients say about living with psychogenic nonepileptic seizures: A systematic synthesis of qualitative studies  Gregg H. Rawlings, Markus Reuber 
Rui Wang, Hong-Zhi Guan, Hai-Tao Ren, Wei Wang, Zhen Hong, Dong Zhou 
W. Owen Pickrell, Arron S. Lacey, Rhys H. Thomas, Ronan A
Self-management interventions for epilepsy in people with intellectual disabilities: A scoping review  Michelle Dannenberg, Silvana E. Mengoni, Bob Gates,
Hans P. Bootsma, Lukas Ricker, Yechiel A
Newer antiepileptic drugs compared to levetiracetam as adjunctive treatments for uncontrolled focal epilepsy: An indirect comparison  Zhu Li-na , Chen.
Fracture risk with use of liver enzyme inducing antiepileptic drugs in people with active epilepsy: Cohort study using the General Practice Research Database 
Francesco Brigo, Raffaele Nardone, Luigi Giuseppe Bongiovanni 
Epileptic spasms: Evidence for oral corticosteroids and implications for low and middle income countries  Sharika V. Raga, Jo M. Wilmshurst  Seizure -
Internet-based knowledge management database for children and adults with epilepsy: A possible model project for evidence-based medicine in the future 
Ali A. Asadi-Pooya, Mehrdad Emami, Alireza Nikseresht 
Oliver Faust, U. Rajendra Acharya, Hojjat Adeli, Amir Adeli 
Peter L. Fisher, Adam J. Noble  Seizure - European Journal of Epilepsy 
Pharmacodynamic and pharmacokinetic interactions of perampanel and other antiepileptic drugs in a rat amygdala kindling model  Ting Wu, Yoko Nagaya, Takahisa.
Early treatment after stroke for the prevention of late epileptic seizures: A report on the problems performing a randomised placebo-controlled double-blind.
Sudden death in epilepsy: Insights from the last 25 years
Milen Pavlović, Nebojša Jović, Tatjana Pekmezović 
Milen Pavlović, Nebojša Jović, Tatjana Pekmezović 
Anina du Toit, Chrisma Pretorius 
HD-tDCS in refractory lateral frontal lobe epilepsy patients
Self reported adverse effects of mono and polytherapy for epilepsy
The effects of levetiracetam on urinary 15f-2t-isoprostane levels in epileptic patients  Hilmi Ozden, Sibel Canbaz Kabay, Aysun Toker, Mehmet Cengiz Ustüner,
Antiepileptic drug use in Austrian nursing home residents
Lindsey Hunter, Peter Sidebotham, Richard Appleton, Colin Dunkley 
Examining a community model of epilepsy care for people with learning disabilities  M. Reuber, J. Gore, J. Wolstenhome, P. Jonas, C. Frankson, C. Murray,
Seizure - European Journal of Epilepsy
Association of the genetic polymorphisms in pre-microRNAs with risk of childhood epilepsy in a Chinese population  Yang Li, Jinqiu Wang, Chunming Jiang,
Eser Basak Sevgi, Serap Saygi, Abdurrahman Ciger 
Seizure - European Journal of Epilepsy
Johan Zelano, Eva Kumlien  Seizure - European Journal of Epilepsy 
Katherine T. Hamilton, Christopher T
A prospective open-labeled trial with levetiracetam in pediatric epilepsy syndromes: Continuous spikes and waves during sleep is definitely a target 
Use and costs of concomitant medicines in epileptic patients in Poland: A 12-month prospective multicentre study  Beata Majkowska-Zwolińska, Joanna Jędrzejczak,
R. Singh, S. Jayapal, S. Goyal, H. Jungbluth, K. Lascelles 
Diego F. Tovar Quiroga, Jeffrey W. Britton, Elaine C. Wirrell 
Tim Wehner, Suganthi Chinnasami, Jan Novy, Gail S. Bell, John S
Anca E. Rapcencu, Dick Lindhout, Saskia Bulk 
Presentation transcript:

Measurement of levetiracetam drug levels to assist with seizure control and monitoring of drug interactions with other anti-epileptic medications (AEMs)  Daria Stepanova, Roy G. Beran  Seizure - European Journal of Epilepsy  Volume 23, Issue 5, Pages 371-376 (May 2014) DOI: 10.1016/j.seizure.2014.02.003 Copyright © 2014 British Epilepsy Association Terms and Conditions

Fig. 1 Blood levels for 23 patients on monotherapy LEV compared with 29 patients on polytherapy including LEV. Seizure - European Journal of Epilepsy 2014 23, 371-376DOI: (10.1016/j.seizure.2014.02.003) Copyright © 2014 British Epilepsy Association Terms and Conditions

Fig. 2 Correlation between total CBZ levels and LEV levels. Seizure - European Journal of Epilepsy 2014 23, 371-376DOI: (10.1016/j.seizure.2014.02.003) Copyright © 2014 British Epilepsy Association Terms and Conditions

Fig. 3 Correlation between total VPA levels and LEV levels. Seizure - European Journal of Epilepsy 2014 23, 371-376DOI: (10.1016/j.seizure.2014.02.003) Copyright © 2014 British Epilepsy Association Terms and Conditions

Fig. 4 Correlation between total LTG and LEV levels. Seizure - European Journal of Epilepsy 2014 23, 371-376DOI: (10.1016/j.seizure.2014.02.003) Copyright © 2014 British Epilepsy Association Terms and Conditions