Wales Neonatal Society Education Day

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Presentation transcript:

Wales Neonatal Society Education Day CARIS 2016 Annual meeting Ysbyty Glan Clwyd Royal Gwent Hospital 12th September 2016

EUROmediCAT euromedicat.eu Prescribing of Antidiabetic Medicines before, during and after Pregnancy: A Study in Seven European Regions (PLOS ONE 18.5.16) (wide variation in treatment for gestational diabetes, increased use of insulin analogues no increased risk of congenital anomaly with insulin analogues) Asthma medication prescribing before, during and after pregnancy: a Study in Seven European regions (BMJ 6.9.16) Risk of congenital anomalies after exposure to asthma medication in the first trimester of pregnancy – a cohort linkage study (BJOG 12.5.16) (small excess risk of major congenital anomaly) Selective serotonin reuptake inhibitor antidepressant use in first trimester pregnancy and risk of specific congenital anomalies: a European register-based study (EUR J Epidemiol 7.7.15) (increased usage since 2004, much higher in UK, raised risk of heart defects but no overall excess of major anomalies)

Could a new test for Down's syndrome soon be made ... - WalesOnline The simple blood test is used to detect the condition and can also pick up Patau’s and Edwards’ syndromes

The chance of the problem being seen on an ultrasound anomaly scan at 18 to 20 weeks Spina bifida 90% (skin or bone not covering the spinal cord) Spina bifida is a fault in the development of the spine and spinal cord which leaves a gap in the spine. The spinal cord connects all parts of the body to the brain. Major heart condition, for example: tetralogy of fallot 40% Tetralogy of fallot is a serious heart condition where the heart has not developed in the same way as a normal heart in the womb. This condition will need surgery usually in the first year of birth. Data from: Welsh Congenital Anomaly Register and Information Service (CARIS) www.caris.wales.nhs.uk/antenatal-detection (Accessed 23/06/2016)

10 year rolling average of Trisomy 13 cases and outcomes – mean of all contributing registries Goel N, Tucker D, Morgan M, 2016

10 year rolling average of Trisomy 13 cases and outcomes – mean of all contributing registries Goel N, Tucker D, Morgan M, 2016

%age Survival in Live births* T13 (countries without ETOP) * Where outcome known = 239/394 Goel N, Tucker D, Morgan M, 2016

%age Survival in Live births* T13 (countries with ETOP) * Where outcome known =1036/1159 Goel N, Tucker D, Morgan M, 2016