Forensic validation of the Genplex SNP typing system—Results of an inter-laboratory study  Esther Musgrave-Brown, David Ballard, Manuel Fondevila Álvarez, Rixun Fang, Cheryl Harrison, Chris Phillips, Yogesh Prasad, Bea Sobrino Rey, Catherine Thacker, Joerg Wiluhn, Angel Carracedo, Peter M. Schneider, Denise Syndercombe Court  Forensic Science International: Genetics Supplement Series  Volume 1, Issue 1, Pages 389-393 (August 2008) DOI: 10.1016/j.fsigss.2007.10.225 Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 1 Results of Genplex and STR typing with varying starting amounts of DNA. Forensic Science International: Genetics Supplement Series 2008 1, 389-393DOI: (10.1016/j.fsigss.2007.10.225) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 2 Results of Genplex and STR typing of UV degraded extracts. Forensic Science International: Genetics Supplement Series 2008 1, 389-393DOI: (10.1016/j.fsigss.2007.10.225) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 3 Results of Genplex and STR typing of putrefied tissue extracts. Forensic Science International: Genetics Supplement Series 2008 1, 389-393DOI: (10.1016/j.fsigss.2007.10.225) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 4 Results of Genplex and STR typing of bone and teeth extracts. Forensic Science International: Genetics Supplement Series 2008 1, 389-393DOI: (10.1016/j.fsigss.2007.10.225) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 5 (a and b) Cluster plot of locus rs2107612 including the mixed extracts. The two homozygote clusters are in red and blue and the heterozygote cluster is in green. Extracts that do not fall into one of the three clusters are indicated by a black x. The two contributors are opposing homozygotes at this locus, and the transition of the mixed extracts between these two clusters can clearly be seen. The 1 to 1 mixture is not detected here as it falls within the heterozygote cluster. (c) Cluster plot of locus rs20562777 including the mixed extracts. The contributors are a heterozygote and a homozygote at this locus, and the transition of the mixed extracts between these two clusters can clearly be seen, although one of the 1 in 10 mixtures was not detected. Forensic Science International: Genetics Supplement Series 2008 1, 389-393DOI: (10.1016/j.fsigss.2007.10.225) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions

Fig. 5 (a and b) Cluster plot of locus rs2107612 including the mixed extracts. The two homozygote clusters are in red and blue and the heterozygote cluster is in green. Extracts that do not fall into one of the three clusters are indicated by a black x. The two contributors are opposing homozygotes at this locus, and the transition of the mixed extracts between these two clusters can clearly be seen. The 1 to 1 mixture is not detected here as it falls within the heterozygote cluster. (c) Cluster plot of locus rs20562777 including the mixed extracts. The contributors are a heterozygote and a homozygote at this locus, and the transition of the mixed extracts between these two clusters can clearly be seen, although one of the 1 in 10 mixtures was not detected. Forensic Science International: Genetics Supplement Series 2008 1, 389-393DOI: (10.1016/j.fsigss.2007.10.225) Copyright © 2008 Elsevier Ireland Ltd Terms and Conditions