Quantitative-Trait-Locus Analysis of Body-Mass Index and of Stature, by Combined Analysis of Genome Scans of Five Finnish Study Groups Markus Perola,

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Quantitative-Trait-Locus Analysis of Body-Mass Index and of Stature, by Combined Analysis of Genome Scans of Five Finnish Study Groups Markus Perola, Miina Öhman, Tero Hiekkalinna, Jenni Leppävuori, Päivi Pajukanta, Maija Wessman, Markku Koskenvuo, Aarno Palotie, Kenneth Lange, Jaakko Kaprio, Leena Peltonen The American Journal of Human Genetics Volume 69, Issue 1, Pages 117-123 (July 2001) DOI: 10.1086/321286 Copyright © 2001 The American Society of Human Genetics Terms and Conditions

Figure 1 LOD scores for QTLs for stature and BMI. The red curve (computed by Solar 1.6.7) represents the multipoint LOD scores for a QTL determining stature, and the blue curve represents the genomewide multipoint LOD score for a QTL determining BMI (both are adjusted for age and for sex). The border of each autosome is indicated by dotted lines. The American Journal of Human Genetics 2001 69, 117-123DOI: (10.1086/321286) Copyright © 2001 The American Society of Human Genetics Terms and Conditions

Figure 2 LOD scores for QTLs for stature and BMI: chromosome 7. The blue curve expands the genomewide multipoint-LOD-score curves in figure 1, to chromosome 7 alone. For comparison, the pink curve represents the results reported by Hirschhorn et al. (2001 [in this issue]) for their Swedish study group, as discussed in the text. The numbers below the horizontal axis indicate distance (in cM) from 7pter. The American Journal of Human Genetics 2001 69, 117-123DOI: (10.1086/321286) Copyright © 2001 The American Society of Human Genetics Terms and Conditions

Figure 3 LOD scores for QTLs for stature and BMI: chromosome 9. The blue curve expands the genomewide multipoint-LOD-score curves in figure 1, to chromosome 9 alone. For comparison, the pink curve represents the results reported by Hirschhorn et al. (2001 [in this issue]) for their Botnian study group, as discussed in the text. The numbers below the horizontal axis indicate distance (in cM) from 9pter. The American Journal of Human Genetics 2001 69, 117-123DOI: (10.1086/321286) Copyright © 2001 The American Society of Human Genetics Terms and Conditions