Murugesan Raju 1 ;Puttur Santhoshkumar 1 ;K. Krishna Sharma 1, 2 ;

Slides:

Advertisements

Similar presentations

OPL GCL OPL GCL Normal Diabetic Isolectin B4 Iba1 Isolectin B4 Iba1 GCL OPL H&E Figure S1. Micorglial cells clustered around perivascular regions labeled.

Advertisements

From: Antimicrobial Efficacy of Contact Lens Care Solutions Against Neutrophil-Enhanced Bacterial Biofilms Trans. Vis. Sci. Tech ;6(2):11. doi: /tvst

Mitochondrial Ferritin Protects Hydrogen Peroxide-Induced Neuronal Cell Damage Guofen Gao 1 ;Nan Zhang 1 ;Yue-Qi Wang 1 ;Qiong Wu 1 ;Peng Yu 1 ;Zhen-Hua.

Scheme 1 Cu(Sal-Gly)(phen) Cu(Sal-Gly)(pheamine) Cu(Sal-Gly)(phepoxy)

Volume 14, Issue 4, Pages (October 2008)

Proteolytic Cleavage of Apolipoprotein E in the Down Syndrome Brain

Murugesan Raju 1 ;Puttur Santhoshkumar 1 ;K. Krishna Sharma 1, 2 ;

Raju Murugesan 1 ;Santhoshkumar Puttur 1 ;Krishna Sharma K. 1, 2 ;

Volume 114, Issue 5, Pages (May 1998)

From: Activation of the Rho/Rho Kinase Signaling Pathway Is Involved in Cell Death of Corneal Endothelium Invest. Ophthalmol. Vis. Sci ;57(15):

AntimiR-30b Inhibits TNF-α Mediated Apoptosis and Attenuated Cartilage Degradation through Enhancing Autophagy Cell Physiol Biochem 2016;40:

Inhibitory effect of polyphenol cyanidin on TNF-α-induced apoptosis through multiple signaling pathways in endothelial cells Jin-Wen Xu, Katsumi Ikeda,

Fig. 3. Effect of JGH43IA on the glutamate-induced DNA fragmentation

From: Elevated Expression of O-GlcNAc–Modified Proteins and O-GlcNAc Transferase in Corneas of Diabetic Goto-Kakizaki Rats Invest. Ophthalmol. Vis. Sci..

Cantharidin Inhibits the Growth of Triple-Negative Breast Cancer Cells by Suppressing Autophagy and Inducing Apoptosis in Vitro and in.

The Combined Effects of Hematoporphyrin Monomethyl Ether-SDT and Doxorubicin on the Proliferation of QBC939 Cell Lines Lei Liang, Sheng Xie, Lin Jiang,

Vascular Endothelial Growth Factor (VEGF)-Mediated Angiogenesis Is Associated with Enhanced Endothelial Cell Survival and Induction of Bcl-2 Expression

Neuroprotective Effect of Didymin on Hydrogen Peroxide-Induced Injury in the Neuronal Membrane System Cells Tissues Organs 2014;199: DOI: /

Date of download: 11/9/2017 Copyright © ASME. All rights reserved.

Mitochondrial Ferritin Protects Hydrogen Peroxide-Induced Neuronal Cell Damage Guofen Gao 1 ;Nan Zhang 1 ;Yue-Qi Wang 1 ;Qiong Wu 1 ;Peng Yu 1 ;Zhen-Hua.

Bovine lactoferricin B induces apoptosis of human gastric cancer cell line AGS by inhibition of autophagy at a late stage W.-R. Pan, P.-W. Chen, Y.-L.

Amanda M. Nelson, Kathryn L. Gilliland, Zhaoyuan Cong, Diane M

Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor–κB and IκBα kinase in human multiple myeloma cells, leading to.

A Novel Cofactor for p300 that Regulates the p53 Response

Induction of apoptosis by CDIP expression.

by Lisa A. Porter, I. Howard Cukier, and Jonathan M. Lee

Progression of aortic valve stenosis: TGF-β1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via.

Transglutaminase 3 Protects against Photodamage

Modification of Alternative Splicing of Mcl-1 Pre-mRNA Using Antisense Morpholino Oligonucleotides Induces Apoptosis in Basal Cell Carcinoma Cells Jeng-Jer.

Volume 134, Issue 4, Pages (April 2008)

Wael M ElShamy, Patrik Ernfors Neuron

Testosterone promotes apoptotic damage in human renal tubular cells

S. Shastry, A.J. Ingram, J.W. Scholey, L.R. James Kidney International

Fertility and Sterility

Figure S1 Nil + CK Nil CK C BIM BCLXL Pro-caspase 3 Cleaved caspase 3

Transglutaminase 3 Protects against Photodamage

Supplementary Figure 2. Effect of IL-32 and siRNA of IL-32 on melanoma, colon and prostate cancer cell growth and apoptosis as well as IL-32 expression.

Jasper G. van den Boorn, Debby Konijnenberg, Trees A. M. Dellemijn, J

Volume 134, Issue 3, Pages (March 2008)

Analysis of antiapoptosis activity of human GM-CSF receptor

Inhibition of glomerular cell apoptosis by heparin

Estrogenic regulation of testicular expression of stem cell factor and c-kit: implications in germ cell survival and male fertility Sara Correia, M.S.,

Volume 67, Issue 1, Pages (January 2005)

P.-A. Hueber, P. Waters, P. Clarke, M. Eccles, P. Goodyer

Nuclear export of endogenous APC in different cell lines.

Volume 120, Issue 1, Pages (January 2005)

Volume 3, Issue 6, Pages (December 2017)

PCB126 induces apoptosis of chondrocytes via ROS-dependent pathways

Jungmook Lyu, Vicky Yamamoto, Wange Lu Developmental Cell

Death Receptor-Independent Apoptosis in Malignant Melanoma Induced by the Small- Molecule Immune Response Modifier Imiquimod Michael P. Schön, B. Gregor.

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells Sonam Dolma, Stephen.

XIAP Regulates Caspase Activity in Degenerating Axons

Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis D.H. Rosenzweig,

Volume 19, Issue 7, Pages (May 2017)

A p38MAPK/HIF-1 Pathway Initiated by UVB Irradiation Is Required to Induce Noxa and Apoptosis of Human Keratinocytes Kris Nys, An Van Laethem, Carine.

Targeted Cleavage of Signaling Proteins by Caspase 3 Inhibits T Cell Receptor Signaling in Anergic T Cells Irene Puga, Anjana Rao, Fernando Macian Immunity

Up-regulation of BDNF induces the neurite outgrowth of SH-SY5Y cells.

Melatonin protects human spermatozoa from apoptosis via melatonin receptor– and extracellular signal–regulated kinase-mediated pathways Javier Espino,

Volume 114, Issue 5, Pages (May 1998)

Effect of M-cadherin RNAi on serum-starvation-induced apoptosis.

Keratinocyte Apoptosis Induced by Ultraviolet B Radiation and CD95 Ligation – Differential Protection through Epidermal Growth Factor Receptor Activation.

Jerry E. Chipuk, Ulrich Maurer, Douglas R. Green, Martin Schuler

Figure 1. Effects of Gal-4 on apoptosis and proliferation of monocytes

Effect of M-cadherin RNAi on apoptosis in confluent C2C12 myoblasts.

Increased pancreatic insulin content and islet size and protection against HFD- and palmitate-induced cell death in PKCδKN-overexpressing mice. Increased.

Figure 1. Effect of a peroxynitrite scavenger on high glucose-induced apoptosis in LLC-PK1 cells. Subconfluent monolayers of LLC-PK1 cells in 6-well tissue.

Evidence for Insertional RNA Editing in Humans

Effects of PS-341 on apoptosis in orthotopic human pancreatic tumors.

Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes Mi Hee Kwack, Young Kwan Sung,

CHL-induced apoptosis in HCT116 cells involves the activation of procaspase-8 and procaspase-6, with cleavage of nuclear lamins. CHL-induced apoptosis.

Presentation transcript:

Murugesan Raju 1 ;Puttur Santhoshkumar 1 ;K. Krishna Sharma 1, 2 ; Lens Endogenous Peptide #cod#x003B1;A66-80 Generates Hydrogen Peroxide and Induces Cell Apoptosis Murugesan Raju 1 ;Puttur Santhoshkumar 1 ;K. Krishna Sharma 1, 2 ; 1 Departments of Ophthalmology and ; 2 Biochemistry, University of Missouri School of Medicine, Columbia, MO65212, USA ; Figure 3. #cod#x003B1;A66-80 peptide--induced cell apoptosis and caspase-3. Peptide-induced cell apoptosis was assessed in the presence and absence of #cod#x003B1;A66-80 peptide or proline-substituted peptide #cod#x003B1;A66-80 pro. A-C and G TUNEL assay, in which the blue stain shows intact nucleus and the red stain indicates fragmented DNA inside the nucleus indicating cell apoptosis. D-F and H Caspase-3 assay, in which the blue stain shows the nucleus and the green stain shows cleaved caspase-3 antibody reactivity. Note that most of the green stain is in the cytoplasmic region. I Effect of catalase on Cos-7 cells treated with #cod#x003B1;A66-80 peptide. Cos-7 cells were cultured and treated as described under methods. Cells were stained with livedead cell staining according to the EarlyTox livedead cell potocol using Spectra Max i3 plate reader. #cod#x003B1;A66-80 10#cod#x000B5;g; Catalase 500 units and #cod#x003B1;A66-8010#cod#x000B5;g +Catalase 500 units The result shown are the avarage of three independent experiments. Aging and Disease,null,8(1),57-70. Doi:10.14336/AD.2016.0805