Successful Treatment of Richter Transformation with Ibrutinib in a Patient with Chronic Lymphocytic Leukemia following Allogeneic Hematopoietic Stem Cell.

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Successful Treatment of Richter Transformation with Ibrutinib in a Patient with Chronic Lymphocytic Leukemia following Allogeneic Hematopoietic Stem Cell Transplant - DOI:10.1159/000477338 Fig. 1. Bone marrow biopsy showing RT. © 2017 The Author(s). Published by S. Karger AG, Basel - CC BY-NC 4.0

Successful Treatment of Richter Transformation with Ibrutinib in a Patient with Chronic Lymphocytic Leukemia following Allogeneic Hematopoietic Stem Cell Transplant - DOI:10.1159/000477338 Fig. 2. a PET scan showing extensive lymphadenopathy in the pelvis and abdomen consistent with the diagnosis of RT. b PET scan after 3 cycles of combination chemotherapy with rituximab-ifosfamide/carboplatin/etoposide (R-ICE). c PET scan showing excellent metabolic response with virtual complete interval resolution of the previously noted extensive FDG avid lymphadenopathy with ibrutinib therapy. © 2017 The Author(s). Published by S. Karger AG, Basel - CC BY-NC 4.0

Successful Treatment of Richter Transformation with Ibrutinib in a Patient with Chronic Lymphocytic Leukemia following Allogeneic Hematopoietic Stem Cell Transplant - DOI:10.1159/000477338 Fig. 3. Bone marrow biopsy showing minimal residual CLL with no evidence of RT. © 2017 The Author(s). Published by S. Karger AG, Basel - CC BY-NC 4.0