The Epidemiology of Hemoglobin Levels in Patients With Type 2 Diabetes

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Presentation transcript:

The Epidemiology of Hemoglobin Levels in Patients With Type 2 Diabetes Merlin C. Thomas, MBChB, PhD, FRACP, Con Tsalamandris, MBBS, Richard J. MacIsaac, MBBS, BSc, PhD, George Jerums, MD, FRACP  American Journal of Kidney Diseases  Volume 48, Issue 4, Pages 537-545 (October 2006) DOI: 10.1053/j.ajkd.2006.06.011 Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 1 Change in Hb levels during 5 years of follow-up in ambulatory individuals with type 2 diabetes (A) with and (B) without anemia at baseline. Grey bars, individuals with a decrease in Hb levels of more than 0.2 g/dL/y (>1 g/dL/5 y); dotted line, mean baseline Hb level. To convert Hb in g/dL to g/L, multiply by 10. American Journal of Kidney Diseases 2006 48, 537-545DOI: (10.1053/j.ajkd.2006.06.011) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 2 A significant decrease in Hb levels is seen more commonly in patients with macrovascular disease (grey bars) than individuals without overt macrovascular disease (white) after adjusting for (A) eGFR and (B) urinary AER. (C) GFR and urinary AER have additive effects on Hb levels. To convert Hb in g/dL to g/L, multiply by 10; GFR in mL/min to mL/s, multiply by 0.01667. American Journal of Kidney Diseases 2006 48, 537-545DOI: (10.1053/j.ajkd.2006.06.011) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 3 Mean change in Hb levels during the 5-year follow-up stratified according to (A) AER and (B) baseline GFR. *P < 0.05 versus AER less than 10 μg/min. #P < 0.05 versus GFR greater than 120 mL/min/1.73 m2. To convert Hb in g/dL to g/L, multiply by 10; GFR in mL/min to mL/s, multiply by 0.01667. American Journal of Kidney Diseases 2006 48, 537-545DOI: (10.1053/j.ajkd.2006.06.011) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

Fig 4 Change in Hb levels during the study period stratified according to age and sex (male, grey; female, white). *Sex difference, P < 0.05. To convert Hb in g/dL to g/L, multiply by 10. American Journal of Kidney Diseases 2006 48, 537-545DOI: (10.1053/j.ajkd.2006.06.011) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions