Upper-Respiratory Viral Infection, Biomarkers, and COPD Exacerbations

Slides:

Advertisements

Similar presentations

Volume 32, Issue 1, Pages (July 1957)

Advertisements

Kanazawa Hiroshi , MD, Hirata Kazuto , MD, Yoshikawa Junichi , MD

Nasal Mask Ventilation in Acute Respiratory Failure

Noninvasive Nasal Mask Ventilation for Acute Respiratory Failure

Antibodies to Collagen in Patients with Idiopathic Pulmonary Fibrosis

Tell-tale Telangiectasias

Colloquium on Therapy of Right Heart Failure

Volume 148, Issue 6, Pages (December 2015)

When to Be Rash About a Fever and Headache

Right-Sided Chest Pain with Progressive Dyspnea

Volume 136, Issue 6, Pages (December 2009)

Myocardial Necrosis in a Patient with Mixed Connective Tissue Disease

Wan-Jie Gu, MSc, Chun-Yin Wei, MSc, Rui-Xing Yin, MD, PhD CHEST

Hyperbaric Oxygenation in Cardiac and Pulmonary Disease

Air Pollution and Chest Disease

Volume 134, Issue 2, Pages (August 2008)

Antibiotic Treatment of Exacerbations of COPD

Volume 122, Issue 4, Pages (October 2002)

Volume 123, Issue 2, Pages (February 2003)

Respiratory Retention of One Micron Particles in Man

Respiratory Nitric Oxide Levels in Experimental Human Influenza

Fever, Skin Eruption, Low Serum Gammaglobulin in a Child with Leukemia

Volume 128, Issue 4, Pages (October 2005)

Volume 129, Issue 1, Pages (January 2006)

Bacterial Infection and the Pathogenesis of COPD

Volume 148, Issue 5, Pages (November 2015)

Frank W. Ewald, MD, FCCP, Albert H. Scherff, MD CHEST

Volume 143, Issue 1, Pages (January 2013)

Volume 151, Issue 3, Pages (March 2017)

Attentional Modulation of Reflex Cough

Exhaled Acetone as a New Biomarker of Heart Failure Severity

Prevalence of Pulmonary Embolism in Acute Exacerbations of COPD

Role of the CHADS2 Score in Acute Coronary Syndromes

Zaid J. Yaqoob, MD, Sadeer G. Al-Kindi, MD, Joe G. Zein, MD CHEST

Acute Pulmonary Exacerbations of Sarcoidosis

Precision Medicine Urgency

Volume 79, Issue 2, Pages (February 1981)

Evgeny Vaschillo, PhD, Bronya Vaschillo, PhD, Paul Lehrer, PhD CHEST

Airway Stenting for Patients With Benign Airway Disease and the Food and Drug Administration Advisory Lund Mark E. , MD, FCCP, Force Seth , MD, FCCP

Exercise-Induced Bronchoconstriction in Healthy Athletes-To the Editor

Acute Myocardial Infarction While Using the Nicotine Patch

Tako-Tsubo Cardiomyopathy: Response

Point: Should Medicare Allow Respiratory Therapists to Independently Practice and Bill for Educational Activities Related to COPD? Yes Thomas M. Fuhrman,

Volume 147, Issue 1, Pages (January 2015)

Henry Maresh, M.D., Joseph J. Klimek, M.D., Richard Quintilioni, M.D.

Detecting Antimycobacterial Antibodies

Imaging for the Management of Community-Acquired Pneumonia

Point: Should We Abandon FEV1/FVC <0

Spread the Word About CHEST in 2015

Possible Role of Statins in COPD-Related Pulmonary Hypertension

Translational Behavioral Research in Respiratory Medicine

Epidemiology of viral respiratory infections in a tertiary care centre in the era of molecular diagnosis, Geneva, Switzerland, 2011–2012 J. Ambrosioni,

Volume 146, Issue 6, Pages (December 2014)

Tako-Tsubo Cardiomyopathy: Response

Volume 134, Issue 2, Pages (August 2008)

F. M. Moesker, J. J. A. van Kampen, A. A. van der Eijk, A. M. C

Volume 92, Issue 1, Pages (July 1987)

Volume 139, Issue 6, Pages (June 2011)

Bedside Calibration Of Pulmonary Artery Catheters

Volume 151, Issue 5, Pages (May 2017)

Do CIs Give You Confidence?

Volume 42, Issue 2, Pages (August 1962)

Calcification of the Coronary Artery

Volume 150, Issue 4, Pages (October 2016)

Infective Exacerbations of COPD

Counterpoint: Should Medicare Allow Respiratory Therapists to Independently Practice and Bill for Educational Activities Related to COPD? No Katherine.

Systemic Inflammation, COPD, and Pulmonary Hypertension

Ann Marie Hart, PhD, FNP The Journal for Nurse Practitioners

New Members of the Editorial Board

Tetracycline Pleurodesis-Associated Acute Renal Failure

Presentation transcript:

Upper-Respiratory Viral Infection, Biomarkers, and COPD Exacerbations Omar Kherad, MD, Laurent Kaiser, MD, Pierre-Olivier Bridevaux, MD, François Sarasin, MD, Yves Thomas, PhD, Jean-Paul Janssens, MD, Olivier T. Rutschmann, MD CHEST Volume 138, Issue 4, Pages 896-904 (October 2010) DOI: 10.1378/chest.09-2225 Copyright © 2010 The American College of Chest Physicians Terms and Conditions

Figure 1 Flowchart of patients included in the study. “Follow-up impossible” refers to patients transferred to another hospital. CHEST 2010 138, 896-904DOI: (10.1378/chest.09-2225) Copyright © 2010 The American College of Chest Physicians Terms and Conditions

Figure 2 Viruses detected by polymerase chain reaction (PCR) in nasopharyngeal samples of 86 patients admitted for acute exacerbations of COPD (AECOPD) (black bars) and 71 patients who completed follow-up (white bars, stable period). RSV = respiratory syncytial virus. CHEST 2010 138, 896-904DOI: (10.1378/chest.09-2225) Copyright © 2010 The American College of Chest Physicians Terms and Conditions

Figure 3 Seasonal variability of viruses detected by reverse transcriptase-polymerase chain reaction (RT-PCR) of nasopharyngeal swabs in patients admitted for AECOPD. See Figure 2 legend for expansion of abbreviations. CHEST 2010 138, 896-904DOI: (10.1378/chest.09-2225) Copyright © 2010 The American College of Chest Physicians Terms and Conditions

Figure 4 Seasonal variability of samples at baseline during admission (A) and at 4-month follow-up (B). CHEST 2010 138, 896-904DOI: (10.1378/chest.09-2225) Copyright © 2010 The American College of Chest Physicians Terms and Conditions

Figure 5 Serum CRP (n = 86) and procalcitonin (PCT) (n = 81) in patients with AECOPD. Five values are missing for PCT (two in the virus-positive group; three in the virus-negative group). Patients with (n = 20) and without bacterial infection (n = 68) identified by semiquantitative bacterial analysis of sputum at admission for AECOPD (A). Patients with (n = 44) and without (n = 42) viral nucleic acids identified by RT-PCR of nasopharyngeal swabs at admission for AECOPD (B). Data are expressed as medians (interquartile range). CHEST 2010 138, 896-904DOI: (10.1378/chest.09-2225) Copyright © 2010 The American College of Chest Physicians Terms and Conditions