Expression of acute-phase cytokines, surfactant proteins, and epithelial apoptosis in small airways of human acute respiratory distress syndrome Ruy.

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Expression of acute-phase cytokines, surfactant proteins, and epithelial apoptosis in small airways of human acute respiratory distress syndrome Ruy Camargo Pires-Neto, PhD, Maina Maria Barbosa Morales, PhD, Tatiana Lancas, PhD, Nicole Inforsato, MD, Maria Irma Seixas Duarte, PhD, Marcelo Britto Passos Amato, PhD, Carlos Roberto Ribeiro de Carvalho, PhD, Luiz Fernando Ferraz da Silva, PhD, Thais Mauad, PhD, Marisa Dolhnikoff, PhD Journal of Critical Care Volume 28, Issue 1, Pages 111.e9-111.e15 (February 2013) DOI: 10.1016/j.jcrc.2012.05.013 Copyright © 2013 Elsevier Inc. Terms and Conditions

Fig. 1 Representative photomicrographs of small airways of the control group (A and C) and patients with ARDS (B and D) stained with anti–IL-8 (A and B) and anti–IL-6 (C,D). There is higher expression of IL-8 in the airway epithelium and a higher number of IL-6– and IL-8–positive inflammatory cells (arrows) in the airway walls in the ARDS group. L, lumen; EP, respiratory epithelium; scale bar, 50 μm. Journal of Critical Care 2013 28, 111.e9-111.e15DOI: (10.1016/j.jcrc.2012.05.013) Copyright © 2013 Elsevier Inc. Terms and Conditions