How does DNA copy itself?

REPLICATION Replication: DNA copies itself Each strand of DNA has the information needed to reconstruct the other half Happens in INTERPHASE Mitosis Meiosis

REPLICATION Semiconservative Replication:

STEP 1: Unwinding DNA Helicase: enzyme that unzips DNA

STEP 2: Base Pairing DNA Polymerase: enzyme that adds new nucleotides to DNA half

STEP 2: Base Pairing Leading strand: Built in same directions as DNA unzips (3’5’)

STEP 2: Base Pairing Lagging strand: Built in opposite direction as DNA unzips (3’5’)

STEP 2: Base Pairing Okazaki fragments: pieces of the lagging strand

STEP 2: Base Pairing DNA ligase: joins Okazaki fragments together

STEP 3: Joining Replication happens in many places on DNA at once DNA ligase joins them together

Complimentary Base Pairing Template Strand: The original strand of DNA that is used to make the new copy.

Animations Replication Process www.lew-port.com/10712041113402793/lib/10712041113402793/animations/DNA%20Replication%20-%20long%20.html http://www.hhmi.org/biointeractive/dna/animations.html