Polymorphisms affecting vitamin D–binding protein modify the relationship between serum vitamin D (25[OH]D3) and food allergy Jennifer J. Koplin, PhD,

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Polymorphisms affecting vitamin D–binding protein modify the relationship between serum vitamin D (25[OH]D3) and food allergy Jennifer J. Koplin, PhD, Noor H.A. Suaini, BSc (Hons), Peter Vuillermin, MBBS, FRACP, PhD, Justine A. Ellis, PhD, Mary Panjari, PhD, Anne-Louise Ponsonby, MBBS, FAFPHM, PhD, Rachel L. Peters, MPH, Melanie C. Matheson, PhD, David Martino, PhD, Thanh Dang, PhD, Nicholas J. Osborne, PhD, Pamela Martin, PhD, Adrian Lowe, PhD, Lyle C. Gurrin, PhD, Mimi L.K. Tang, MD, PhD, Melissa Wake, MD, FRACP, Terry Dwyer, PhD, John Hopper, PhD, Shyamali C. Dharmage, MBBS, MSc, MD, PhD, Katrina J. Allen, MBBS, BMedSc, FRACP, PhD Journal of Allergy and Clinical Immunology Volume 137, Issue 2, Pages 500-506.e4 (February 2016) DOI: 10.1016/j.jaci.2015.05.051 Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Participation in assessments at age 1 year. OFC, Oral food challenge; SNP, single nucleotide protein; SPT, skin prick test. *Note that some infants fell into more than 1 of these categories. Of these infants, 44 had at least 1 negative challenge to a food to which they were sensitized; however, their full status was unknown because they did not undergo a challenge to all the foods to which they were sensitized. †A total of 73 infants were allergic to more than 1 food. Journal of Allergy and Clinical Immunology 2016 137, 500-506.e4DOI: (10.1016/j.jaci.2015.05.051) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E2 Participation in egg allergy longitudinal study. OFC, Oral food challenge. *Note: 101 of these 105 infants had vitamin D levels measured at both ages 1 and 2 years and were therefore also included in the age 1 year analysis. Journal of Allergy and Clinical Immunology 2016 137, 500-506.e4DOI: (10.1016/j.jaci.2015.05.051) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions