Fig. 5. The measurement of phosphorylation of p53 level in N2A cells under high glucose condition and agmatine treatment. (A, B) p53 phosphorylation levels.

Slides:



Advertisements
Similar presentations
A) 80 b) 53 c) 13 d) x 2 = : 10 = 3, x 3 = 309.
Advertisements

Figure 1.1 The observer in the truck sees the ball move in a vertical path when thrown upward. (b) The Earth observer views the path of the ball as a parabola.
H1299 Vector H1648 TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector H1648 TUSC2 TUSC2 -ER 2.3 uM ER H1299 Vector TUSC2 TUSC2.
Fig. S1 1 Oxygen consumption rate (pmol/sec/10⁶cells) shLKB1#1 control * untreated 25 μM erlotinib H358 Vector LKB1 Oxygen consumption rate (pmol/sec/10⁶cells)
Fig. 2. The expression of pKr-2 in the substantia nigra (SN) of patients with Parkinson's disease (PD). (A, B) Western blot analysis for pKr-1-2 and pKr-2,
Metformin prevents glucotoxicity by alleviating oxidative and ER stress–induced CD36 expression in pancreatic beta cells  Jun Sung Moon, Udayakumar Karunakaran,
Fig. 2. Effects of lobeglitazone on profibrotic gene expression in kidneys of unilateral ureteral obstruction (UUO) mice. (A) Representative Western blot.
Fig. 4. miR-326, miR-330, and miR-3099 bound to the GFAP 3'-UTR and regulated GFAP expression. (A) Schematic diagram of potential binding sequence (seed.
Fig. 5. Agmatine suppressed JNK and P38 MAPK phosphorylation after TBI
Fig. 2. Neuroprotective effects of ex-4 through the G protein-coupled GLP-1 receptor. (A) Infarct volume was assessed by TTC staining after tMCAO in rats.
Fig. 4. TGF-α is one of the major cytokines in M2 conditioned media
Cell Physiol Biochem 2013;32: DOI: /
From: PTX3 Controls Activation of Matrix Metalloproteinase 1 and Apoptosis in Conjunctivochalasis Fibroblasts Invest. Ophthalmol. Vis. Sci ;53(7):
Fig. 5. Effect of JGH43IA on the expression of neuronal survival and death related proteins. Western blot analysis of neuronal cell survival and death.
Fig. 2. Expressions of TMEM16A and MUC5AC proteins in dissociated human sinonasal epithelium. (A) The expression of TMEM16A protein was detected by Western.
Figure 3. Elevation of p53 and its acetylation after treatment with FK866 and nicotinamide adenine dinucleotide (NAD+). Cells were treated for 72 hours.
Fig. 5. Levels of apoptosis-associated proteins following treatment with parthenolide (PT) and balsalazide. HCT116 cell lysates were prepared after treatment.
Fig. 9. Treatment of flagellin increased cell survival in hypoxic conditions. (A) After 2 h OGD, cell cytotoxicity levels were measured by a LDH assay.
Fig. 2. Infection by lentivirus
Volume 10, Pages (August 2016) Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion 
Fig S1 Mannitol pre-treatment dosen’t affect RANKL-induced macrophage activation. A B To study the effect of mannitol pre-treatment, as a control for osmotic.
Heat Shock Protein Expression in Rat Skeletal Muscle After Repeated Applications of Pulsed and Continuous Ultrasound  Ethne L. Nussbaum, PhD, PT, Marius.
Expression of phosphorylated BNP, HIF-2 alpha and beta actin proteins in the primary tumour tissues using western blotting. Expression of phosphorylated.
Interferon (IFN)-Induced Protein 35 (IFI35), a Type I Interferon-Dependent Transcript, Upregulates Inflammatory Signaling Pathways by Activating Toll-Like.
H. Wang, Y. Dong, J. Zhang, Z. Xu, G. Wang, C. A. Swain, Y. Zhang, Z
(a) (b) SUPPLEMENTARY FIGURE 1:
DHEA(S) and Allo induced the expression of the antiapoptotic Bcl-2 proteins in serum-deprived PC12 cells. DHEA(S) and Allo induced the expression of the.
Fig. 1. Potent and selective down-regulation of KRAS mRNA and protein by AZD4785 in vitro and in vivo. Potent and selective down-regulation of KRAS mRNA.
pY-Tie2 (IP with anti-Tie2) Tie2 P-RET RET P-KIT KIT GAPDH P-AXL AXL
Expression changes of specific epigenetic-controlled tumor-related genes by the prenatal/maternal BSp treatment. qRT-PCR and Western blot analysis were.
Fig. 1. Chlamydia infection causes elevated levels of sortilin.
TP53 western blot of primary cultured tail cells from both wild-type (WT) and Tp53Δ11/Δ11 (−/−) rats. TP53 western blot of primary cultured tail cells.
Muscle AMPK activity (A), AMPK protein (B) and representative AMPK western blot (C) in goldfish exposed to normoxia (N; ∼9.5 mg O2l–1; open squares) and.
Liver AMPK activity (A), protein AMPK (B) and representative AMPKα western blot (C) in goldfish exposed to normoxia (N; ∼9.5 mg O2l–1; open squares) and.
Fig. 3. (A) Effect of bilobetin on the protein level for lipogenic regulators. Simian virus 40 T (SV40T)-transformed sebocytes were treated with insulin-like.
Expression of angiotensin converting enzyme (ACE; A) and transforming growth factor β (TGF-β; B) in lung tissue of hibernating hamsters. Expression of.
Effect of 14 hit compounds on SMN protein expression in type I SMA patient fibroblast cells (GM03813). Effect of 14 hit compounds on SMN protein expression.
Src tethers Cas to adhesion complexes.
Validation of DNMT3A splice variant expression.
JAK3A572V mutation causes constitutive JAK3 activity and IL-2–independent proliferation of NKTCL cells. JAK3A572V mutation causes constitutive JAK3 activity.
Fig. 3. PLD2 and PARN overexpression affects PARN and PLD2 protein and gene expression. PLD2 and PARN overexpression affects PARN and PLD2 protein and.
Fig. 3. Effects of Tec on IL-1β-induced apoptosis in chondrocytes.
Stimulation of cells with FFAR4 agonist.
The effect of purified IgG from healthy controls or patients with lupus nephritis on tyrosine phosphorylation in podocytes at two different IgG concentrations.
Fig. 2. Acetylation stiffens primary cilia.
Tyrosine phosphorylation of proteins in podocyte lysates following exposure to healthy or lupus nephritis plasma. Tyrosine phosphorylation of proteins.
Fig. 4. Reduction of apoptosis and autophagic stress by treatment with silibinin in the KA-treated hippocampus. (A, B) Double-immunofluorescence staining.
Kinetics of BDNF-induced Erk, Akt and PLCγ activation in the presence of 15 mM NaCl or 15 mM KCl. Representative western blots (A) and quantitative plots.
Fig. 5. Anti-inflammatory effects of silibinin on KA treatment in the hippocampus. (A) Representative coronal sections of the hippocampal CA1 region following.
Aβ-mediated Ras-MAPK signaling and Cyclin D1 expression in B103 cells are dependent on APP expression and can be reversed with MEK or Ras inhibition. Aβ-mediated.
Fig. 3. Western blot analyses of LGR5 and Wnt/β-catenin signaling pathway proteins in AH of PDR patients and control subjects. AH samples were obtained.
Fig. 7. Effect of CM from hASCs and melatonin-treated hASCs on protein expression in cisplatin-exposed HK-2 cells. HK-2 cells were exposed to cisplatin.
Fig. 5. Western blot analyses for PECAM-1 (A), phosphor-eNOS and total eNOS (B), and phosphor-MYPT-1 and total MYPT-1 (C). β-actin serves as a control.
Fig. 4. Effects of natriuretic peptide receptor 2 (NPR2) knockdown on cells apoptosis in mouse Leydig cells. (A) Relative mRNA expression of cell apoptosis.
Fig. 1. Changes in hippocampal matrix metalloproteinase-9 (MMP-9) and angiopoietin-2 (ANG-2) expression over time following bilateral common carotid artery.
FOXO3a phosphorylation and expression.
Fig. 4. The expression of TRAF6 in the PBMCs of the AR children after a 3-month SIT treatment. (A) Representative Western blot analysis of TRAF6 in the.
BME treatment increases granzyme B expression in NK 3.3 cells.
Fig. 8 C9orf72 knockdown results in an increase in autophagic flux.
A, one-step viral growth curves: RT treatment increased the virus yield in MV-CEA–treated U87 cells by up to 2 log as compared with MV-CEA infection only.
Effect of SFN on the protein expression of Nrf2, HO-1, and NQO1 in JB6-shMock and JB6-shNrf2 cells. Effect of SFN on the protein expression of Nrf2, HO-1,
Fig. 4. Chronic microwave treatment produced changes in glucose and corticosterone levels in blood. (A) Blood glucose levels of mice subjected to chronic.
Fig. 3. KMS99220 inhibits activation of NFκB signaling via HO-1 induction. (A) BV2 cells were treated with 10 µM KMS99220 for 1 h, and then treated with.
The combination of trastuzumab and SU11274 abrogate Akt phosphorylation. The combination of trastuzumab and SU11274 abrogate Akt phosphorylation. Serum-starved.
Fig. 4. Dopaminergic signaling pathways are impaired in Ewsr1 KO (−/−) mice at 3 weeks of age. (A) qPCR analysis showed that Th mRNA was significantly.
Fig. 3. hALDH1L1 promoter-driven Cre recombinase-mediated tdTomato expression in BLA. (A) Low magnification images of injection area in amygdala. Each.
Effect of bevacizumab on the proliferation of A2780 cells.
Effect of SFN on the total activity and protein expression of HDACs in JB6 P+ cells. Effect of SFN on the total activity and protein expression of HDACs.
Effect of 6-SHO on mouse prostate cancer HMVP2 cells.
Determination of Per2 (left), MTNR1A (middle), and ERβ (right) protein expression levels in mammary tissues of rats sacrificed at ZT12. Determination of.
Presentation transcript:

Fig. 5. The measurement of phosphorylation of p53 level in N2A cells under high glucose condition and agmatine treatment. (A, B) p53 phosphorylation levels were measured by using western blotting. In agmatine treatment group, the protein level of p-p53 was increased compared to the normal control group. The high glucose injured group showed lesser protein levels of p-p53 than normal control group. In high glucose condition, agmatine treatment increased the phosphorylation of p53 in the cells. Data were expressed as mean±S.E.M, and each experiment included 3 repeats per condition. beta-actin was used as an internal control. Differences were considered significant at *p<0.05, **p<0.001. Fig. 5. The measurement of phosphorylation of p53 level in N2A cells under high glucose condition and agmatine treatment. (A, B) p53 phosphorylation levels were measured by using western blotting. In agmatine treatment group, the protein level of p-p53 was increased compared to the normal control group. The high glucose injured group showed lesser protein levels of p-p53 than. . . Exp Neurobiol. 2016 Feb;25(1):24-32. http://dx.doi.org/10.5607/en.2016.25.1.24