A unique case of distant skin metastasis from chondroid chordoma

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Presentation transcript:

A unique case of distant skin metastasis from chondroid chordoma Maria C. Riesco-Martínez, MD, MSc, Lucía Parrilla-Rubio, MD, MSc, Ana B. Enguita-Valls, MD, Ana M. Delgado-Márquez, MD, Sherry A. Ruste, MD, MSc, Jose-A. López-Martín, MD, MSc JAAD Case Reports Volume 2, Issue 1, Pages 63-66 (January 2016) DOI: 10.1016/j.jdcr.2015.11.014 Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Skin metastases from chondroid chordoma on the cheek and back. JAAD Case Reports 2016 2, 63-66DOI: (10.1016/j.jdcr.2015.11.014) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Staining of skin metastasis from chondroid chordoma. A, Skin with many vacuolated cells in the dermis. B, cells present a clear cytoplasm with some cells with eosinophilic cytoplasm on a chondral stroma. Some of the cells present the characteristic physaliferous cytoplasm. (A and B, Hematoxylin-eosin stain; original magnifications: A, ×2; B, ×10.) JAAD Case Reports 2016 2, 63-66DOI: (10.1016/j.jdcr.2015.11.014) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Immunohistochemistry staining. Skin metastasis from chordoma positive for pancytokeratines (A), S100 (B), epithelial membrane antigen (C), and vimentin (D). JAAD Case Reports 2016 2, 63-66DOI: (10.1016/j.jdcr.2015.11.014) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions