Allergy and Aging: An Old/New Emerging Health Issue

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Presentation transcript:

Allergy and Aging: An Old/New Emerging Health Issue De Martinis#cod#x0002A; Massimo;Maddalena Sirufo Maria;Ginaldi Lia; Department of Life, Health, #cod#x00026; Environmental Sciences, University of L#cod#x00027;Aquila, L#cod#x00027;Aquila, Italy ; Figure 1. Age-related changes underlying allergy in the elderly. The onset of allergic diseases in the elderly is driven by cell aging at large and by immunosenescence and tissue structure modifications typical of advanced age. The figure illustrates the age-related functional and structural changes in upper and lower airways, skin and gut underlying the onset of allergy reactions in the elderly. ACE = angiotensin-converting-enzyme; CHF = chronic heart failure; COPD = chronic obstructive pulmonary disease; GERD = gastroesophageal reflux disease; NSAIDs = nonsteroidal anti-inflammatory drug; PPI = proton pump inhibitors. null,null,0(0),null-null. Doi:10.14336/AD.2016.0831