From: Quantification of Oxygen Consumption in Retina Ex Vivo Demonstrates Limited Reserve Capacity of Photoreceptor Mitochondria Invest. Ophthalmol. Vis.

Slides:

Advertisements

Similar presentations

From: In Vivo Measurement of Blood Velocity in Human Major Retinal Vessels Using the Laser Speckle Method Invest. Ophthalmol. Vis. Sci ;52(1):87-92.

Advertisements

From: Enhanced Motion Aftereffects in Migraine Are Related to Contrast Sensitivity: Implications for Models of Differences in Precortical/Cortical Function.

From: Advantages of Using Mitochondrial 16S rDNA Sequences to Classify Clinical Isolates of Acanthamoeba Invest. Ophthalmol. Vis. Sci ;44(3):

Invest. Ophthalmol. Vis. Sci ;49(7): doi: /iovs Figure Legend:

From: The Effect of Ambient Ozone on Unsaturated Tear Film Wax Esters

From: Postnatal Gene Expression in the Normal Mouse Cornea by SAGE

Invest. Ophthalmol. Vis. Sci ;52(1): doi: /iovs Figure Legend:

From: Topical Pazopanib Blocks VEGF-Induced Vascular Leakage and Neovascularization in the Mouse Retina but Is Ineffective in the Rabbit Invest. Ophthalmol.

From: Systemic and Intravitreal Delivery of Dendrimers to Activated Microglia/Macrophage in Ischemia/Reperfusion Mouse Retina Invest. Ophthalmol. Vis.

From: Lectin from Agaricus bisporus Inhibited S Phase Cell Population and Akt Phosphorylation in Human RPE Cells Invest. Ophthalmol. Vis. Sci ;53(12):

From: Meibomian Gland Dysfunction Model in Hairless Mice Fed a Special Diet With Limited Lipid Content Invest. Ophthalmol. Vis. Sci ;57(7):

From: Insulin-like Growth Factor-1 and Cardiotrophin 1 Increase Strength and Mass of Extraocular Muscle in Juvenile Chicken Invest. Ophthalmol. Vis. Sci..

From: Targeted Administration into the Suprachoroidal Space Using a Microneedle for Drug Delivery to the Posterior Segment of the Eye Invest. Ophthalmol.

From: Microbead-Induced Ocular Hypertensive Mouse Model for Screening and Testing of Aqueous Production Suppressants for Glaucoma Invest. Ophthalmol. Vis.

From: Stereotactic Radiosurgery for AMD: A Monte Carlo–Based Assessment of Patient-Specific Tissue Doses Invest. Ophthalmol. Vis. Sci ;52(5):

From: Inhibition of Apoptosis and Reduction of Intracellular pH Decrease in Retinal Neural Cell Cultures by a Blocker of Carbonic Anhydrase Invest. Ophthalmol.

From: Which Members of a Community Need Antibiotics to Control Trachoma? Conjunctival Chlamydia trachomatis Infection Load in Gambian Villages Invest.

From: Experimental Anterior Ischemic Optic Neuropathy in Diabetic Mice Exhibited Severe Retinal Swelling Associated With VEGF Elevation Invest. Ophthalmol.

Invest. Ophthalmol. Vis. Sci ;53(4): doi: /iovs Figure Legend:

From: Analysis of Kinesin-2 Function in Photoreceptor Cells Using Synchronous Cre-loxP Knockout of Kif3a with RHO-Cre Invest. Ophthalmol. Vis. Sci ;47(11):

Invest. Ophthalmol. Vis. Sci ;48(1): doi: /iovs Figure Legend:

Invest. Ophthalmol. Vis. Sci ;57(13): doi: /iovs Figure Legend:

Invest. Ophthalmol. Vis. Sci ;58(1): doi: /iovs Figure Legend:

From: Comparison of High-Resolution Melting Analysis with Denaturing High-Performance Liquid Chromatography for Mutation Scanning in the ABCA4 Gene Invest.

Invest. Ophthalmol. Vis. Sci ;49(4): doi: /iovs Figure Legend:

From: Retina-Specific Protein Fascin 2 Is an Actin Cross-linker Associated with Actin Bundles in Photoreceptor Inner Segments and Calycal Processes Invest.

From: High Glucose Induces Mitochondrial Dysfunction in Retinal Müller Cells: Implications for Diabetic Retinopathy Invest. Ophthalmol. Vis. Sci ;58(7):

From: Uvemaster: A Mobile App-Based Decision Support System for the Differential Diagnosis of Uveitis Invest. Ophthalmol. Vis. Sci ;58(10):

From: Phenotypes and Biomarkers of Diabetic Retinopathy

From: Refractive Error, Ocular Biometry, and Lens Opalescence in an Adult Population: The Los Angeles Latino Eye Study Invest. Ophthalmol. Vis. Sci ;46(12):

From: Hypoxic-Preconditioned Bone Marrow Stem Cell Medium Significantly Improves Outcome After Retinal Ischemia in Rats Invest. Ophthalmol. Vis. Sci..

Invest. Ophthalmol. Vis. Sci ;57(4): doi: /iovs Figure Legend:

Invest. Ophthalmol. Vis. Sci ;48(12): doi: /iovs Figure Legend:

From: Effects of Sildenafil and Tadalafil on Intraocular Pressure in Sheep: Implications for Aqueous Humor Dynamics Invest. Ophthalmol. Vis. Sci ;51(6):

Figure Legend: From: High-Fat Diet–Induced Retinal Dysfunction

From: Macular Choroidal Thickness and Volume in Normal Subjects Measured by Swept-Source Optical Coherence Tomography Invest. Ophthalmol. Vis. Sci ;52(8):

From: Error Correction and Quantitative Subanalysis of Optical Coherence Tomography Data Using Computer-Assisted Grading Invest. Ophthalmol. Vis. Sci..

Invest. Ophthalmol. Vis. Sci ;58(4): doi: /iovs Figure Legend:

From: Role of Caveolin-1 for Blocking the Epithelial-Mesenchymal Transition in Proliferative Vitreoretinopathy Invest. Ophthalmol. Vis. Sci ;58(1):

From: One-Year Outcome of 49-Channel Suprachoroidal–Transretinal Stimulation Prosthesis in Patients With Advanced Retinitis Pigmentosa Invest. Ophthalmol.

From: Mitochondrial Dynamics Regulate Growth Cone Motility, Guidance, and Neurite Growth Rate in Perinatal Retinal Ganglion Cells In Vitro Invest. Ophthalmol.

Invest. Ophthalmol. Vis. Sci ;54(1): doi: /iovs Figure Legend:

Invest. Ophthalmol. Vis. Sci ;45(3): doi: /iovs Figure Legend:

From: An Experimental Protocol of the Model to Quantify Traction Applied to the Retina by Vitreous Cutters Invest. Ophthalmol. Vis. Sci ;51(8):

From: Epigenetic Modification of Sod2 in the Development of Diabetic Retinopathy and in the Metabolic Memory: Role of Histone Methylation Invest. Ophthalmol.

From: Noninvasive and Simultaneous Imaging of Layer-Specific Retinal Functional Adaptation by Manganese-Enhanced MRI Invest. Ophthalmol. Vis. Sci ;47(6):

From: Protection of the Retina by Rapid Diffusion of Hydrogen: Administration of Hydrogen-Loaded Eye Drops in Retinal Ischemia–Reperfusion Injury Invest.

From: In Vivo Imaging of Microscopic Structures in the Rat Retina

Invest. Ophthalmol. Vis. Sci ;56(12): doi: /iovs Figure Legend:

From: Cfh Genotype Interacts With Dietary Glycemic Index to Modulate Age-Related Macular Degeneration-Like Features in Mice Invest. Ophthalmol. Vis. Sci..

Invest. Ophthalmol. Vis. Sci ;57(6): doi: /iovs Figure Legend:

From: Brillouin Microscopy of Collagen Crosslinking: Noncontact Depth-Dependent Analysis of Corneal Elastic Modulus Invest. Ophthalmol. Vis. Sci ;54(2):

From: Two-Photon Autofluorescence Imaging Reveals Cellular Structures Throughout the Retina of the Living Primate Eye Invest. Ophthalmol. Vis. Sci ;57(2):

Invest. Ophthalmol. Vis. Sci ;46(4): doi: /iovs Figure Legend:

From: Neural Stem Cells Derived by Small Molecules Preserve Vision

From: Source-Dependent Intracellular Distribution of Iron in Lens Epithelial Cells Cultured Under Normoxic and Hypoxic Conditions Invest. Ophthalmol. Vis.

From: EphrinB2–EphB4 Signals Regulate Formation and Maintenance of Funnel-Shaped Valves in Corneal Lymphatic Capillaries Invest. Ophthalmol. Vis. Sci..

Invest. Ophthalmol. Vis. Sci ;52(9): doi: /iovs Figure Legend:

Invest. Ophthalmol. Vis. Sci ;57(2): doi: /iovs Figure Legend:

From: Higher Contrast Requirement for Letter Recognition and Macular RGC+ Layer Thinning in Glaucoma Patients and Older Adults Invest. Ophthalmol. Vis.

From: Diffusion Tensor Imaging Detected Optic Nerve Injury Correlates with Decreased Compound Action Potentials after Murine Retinal Ischemia Invest. Ophthalmol.

From: Cold-Sensitive Corneal Afferents Respond to a Variety of Ocular Stimuli Central to Tear Production: Implications for Dry Eye Disease Invest. Ophthalmol.

From: Ghrelin Attenuates Retinal Neuronal Autophagy and Apoptosis in an Experimental Rat Glaucoma Model Invest. Ophthalmol. Vis. Sci ;58(14):

From: Scanning Laser Polarimetry with Variable Corneal Compensation: Identification and Correction for Corneal Birefringence in Eyes with Macular Disease.

From: High Resolution OCT Quantitative Analysis of the Space Between the IOL and the Posterior Capsule During the Early Cataract Postoperative Period Invest.

From: Development and Characterization of an Adult Retinal Explant Organotypic Tissue Culture System as an In Vitro Intraocular Stem Cell Transplantation.

From: Retinal Structure of Birds of Prey Revealed by Ultra-High Resolution Spectral-Domain Optical Coherence Tomography Invest. Ophthalmol. Vis. Sci..

From: Cellular Reorganization in the Human Retina during Normal Aging

Invest. Ophthalmol. Vis. Sci ;55(7): doi: /iovs Figure Legend:

From: Fasudil, a Clinically Used ROCK Inhibitor, Stabilizes Rod Photoreceptor Synapses after Retinal Detachment Trans. Vis. Sci. Tech ;6(3):22. doi: /tvst

Presentation transcript:

From: Quantification of Oxygen Consumption in Retina Ex Vivo Demonstrates Limited Reserve Capacity of Photoreceptor Mitochondria Invest. Ophthalmol. Vis. Sci.. 2015;56(13):8428-8436. doi:10.1167/iovs.15-17901 Figure Legend: Comparison of OCR traces in basic salt solution and with combinations of substrates (6 mM D-glucose, 0.15 mM pyruvate,1 mM lactate, 0.5 mM L-glutamine, 2 mM β-hydroxybutyrate), as indicated. We normalized OCR to mitochondrial cytochrome a content. Arrows indicate the injection of uncoupler or rotenone (1 μM final concentration) in the sample well. n = 8 retinal samples from 2 to 3 mice. Error bars: SEM. Date of download: 10/26/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.