Case History Age / Sex : 59 / F C. C : Pancreatic mass

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Case History Age / Sex : 59 / F C. C : Pancreatic mass P. I : Left leg edema (1 Month) Mass was detected at local clinic P. Hx : 1975 Thyroid tumor op. 1980 Uterine myoma op 1995 Hypertension S. Hx : No alcohol dringking Lab : Amylase, lipase : normal Autoantibodies : negative

CD20 CD3

Kappa Lambda

Chronic Pancreatitis Alcohol- and obstruction-related chronic pancreatitis Hereditary pancreatitis Autoimmune pancreatitis Idiopathic chronic pancreatitis with periductal lymphoplasmacytic infiltration Lymphoplasmacytic sclerosing pancreatitis

Idiopathic Chronic Pancreatitis with Periductal Lymphoplasmacytic Infiltration Am J Sur Pathol 27 (8) : 1119-1127, 2003 1. LPSP (Lymphoplasmacytic sclerosing pancreatitis Involvement and replacement of exocrine pancreas by a lymphoplasmacytic fibrinoinflammatory process Single file infiltrates between thick, swirling collagen fibers Rare neutophils Periductal inflammation Rare epithelial damae Obliterative pnlebitis Lymphoid follicles 2. IDCP (Idiopathic ductcentric chronic pancreatitis) Prominent lobular inflammation consisting of edema and infiltrating neutrophils, lymphocytes, and plasma cells Inflammatory infiltrates in fibrotic area and adipose tissue are not prominent Neutrophils frequently involves the duct epithelium and lumen

Lymphoplasmacytic sclerosing pancreatitis Tentative Diagnosis Lymphoplasmacytic sclerosing pancreatitis