CARIS annual review What’s new ?

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Presentation transcript:

CARIS annual review What’s new ? Ty Dewi Sant Cardiff University 6th November 2013

Research involving CARIS Research Programme Research involving CARIS Pharmacovigilance Drugs taken in the first trimester Antiepileptics – ongoing since 2008 EuroMedicat – 2011-2014 Insulin Antiasthmatics SSRIs Thyroxine

Patau syndrome (T13) rates by maternal age 3 year rolling rates per 10,000 total births. CARIS data 1998 to 2011

Further questions Is this decline real or just related to reporting? Research Programme Further questions Is this decline real or just related to reporting? Is it significant? What has changed over the years (assisted conception, folic acid, paternal age)? Does it occur in other anomalies?

Down syndrome (T21) rates by maternal age Rates per 10,000 total births. CARIS data 1998 to 2011

Edwards syndrome (T18) rates by maternal age 3 year rolling rates per 10,000 total births. CARIS data 1998 to 2011

Baby hearts project Risk factors for congenital heart disease University of Ulster Swansea & Cardiff Universities CARIS

Preconceptual Counselling Reasons why high congenital anomaly rates in Wales obesity epidemic smoking, alcohol, drugs medical disorders maternal deaths due to chronic conditions Barriers why not unplanned pregnancy not trying/not preventing lack of public awareness

Survey of 100 pregnant women Pre–conceptual counselling? Text, tables and graphs as appropriate. Visible colours. 12

Would they have liked to receive PCC? Results Would they have liked to receive PCC? N = 74 Text, tables and graphs as appropriate. Visible colours. 13

Thank you for your help and contributions to Thank you for your help and contributions to CARIS over the past 15 years