Volume 152, Issue 4, Pages (October 2017)

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Volume 152, Issue 4, Pages 821-832 (October 2017) Morphine Use in the ED and Outcomes of Patients With Acute Heart Failure Òscar Miró, MD, PhD, Víctor Gil, MD, Francisco J. Martín-Sánchez, MD, PhD, Pablo Herrero-Puente, MD, PhD, Javier Jacob, MD, PhD, Alexandre Mebazaa, MD, PhD, Veli-Pekka Harjola, MD, PhD, José Ríos, MSc, Judd E. Hollander, MD, PhD, W. Frank Peacock, MD, PhD, Pere Llorens, MD, PhD Marta Fuentes, Cristina Gil, María José Pérez-durá, Eva Salvo, José Vallés, Rosa Escoda, Carolina Xipell, Carolina Sánchez, José Pavón, Ana Bella Álvarez, Antonio Noval, José M. Torres, Maria Luisa López-Grima, Amparo Valero, Alfons Aguirre, Maria Àngels Pedragosa, Maria Isabel Alonso, Helena Sancho, Paco Ruiz, Antonio Giménez, José Miguel Franco, Sergio Pardo, Ana Belen Mecina, Josep Tost, Jordi Fabregat, Susana Sánchez, Pascual Piñera, Raquel Torres Garate, Aitor Alquezar, Miguel Alberto Rizzi, Fernando Richard, Javier Lucas, Irene Cabello, Álex Roset, Esther Rodríguez-Adrada, Guillermo Llopis García, José Manuel Garrido Òscar Miró, MD, PhD, Víctor Gil, MD, Francisco J. Martín-Sánchez, MD, PhD, Pablo Herrero-Puente, MD, PhD, Javier Jacob, MD, PhD, Alexandre Mebazaa, MD, PhD, Veli-Pekka Harjola, MD, PhD, José Ríos, MSc, Judd E. Hollander, MD, PhD, W. Frank Peacock, MD, PhD, Pere Llorens, MD, PhD Marta Fuentes, Cristina Gil, María José Pérez-durá, Eva Salvo, José Vallés, Rosa Escoda, Carolina Xipell, Carolina Sánchez, José Pavón, Ana Bella Álvarez, Antonio Noval, José M. Torres, Maria Luisa López-Grima, Amparo Valero, Alfons Aguirre, Maria Àngels Pedragosa, Maria Isabel Alonso, Helena Sancho, Paco Ruiz, Antonio Giménez, José Miguel Franco, Sergio Pardo, Ana Belen Mecina, Josep Tost, Jordi Fabregat, Susana Sánchez, Pascual Piñera, Raquel Torres Garate, Aitor Alquezar, Miguel Alberto Rizzi, Fernando Richard, Javier Lucas, Irene Cabello, Álex Roset, Esther Rodríguez-Adrada, Guillermo Llopis García, José Manuel Garrido CHEST Volume 152, Issue 4, Pages 821-832 (October 2017) DOI: 10.1016/j.chest.2017.03.037 Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 1 Flow chart of patient inclusion in the present study. AHF = acute heart failure. CHEST 2017 152, 821-832DOI: (10.1016/j.chest.2017.03.037) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 2 Analysis of primary outcome using survival curves for propensity score-matched patients treated with and without IV morphine in the ED. HR = hazard ratio. CHEST 2017 152, 821-832DOI: (10.1016/j.chest.2017.03.037) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 3 Analysis of secondary end points regarding intermediate mortality for propensity score-matched patients treated with and without IV morphine in the ED. CHEST 2017 152, 821-832DOI: (10.1016/j.chest.2017.03.037) Copyright © 2017 American College of Chest Physicians Terms and Conditions

Figure 4 Sensitivity analysis stratifying 30-day mortality risk by sex, age, need for ventilatory support, and vasoactive drugs for propensity score-matched patients treated with and without IV morphine in the ED. CHEST 2017 152, 821-832DOI: (10.1016/j.chest.2017.03.037) Copyright © 2017 American College of Chest Physicians Terms and Conditions