Volume 138, Issue 3, Pages 621-627 (September 2010) Interactions Between COPD and Outcomes After Percutaneous Coronary Intervention Tomas Konecny, MD, Krishen Somers, Marek Orban, MD, Yuki Koshino, MD, Ryan J. Lennon, MS, Paul D. Scanlon, MD, FCCP, Charanjit S. Rihal, MD CHEST Volume 138, Issue 3, Pages 621-627 (September 2010) DOI: 10.1378/chest.10-0300 Copyright © 2010 The American College of Chest Physicians Terms and Conditions
Figure 1 Patients with COPD suffer from worse outcomes after percutaneous coronary intervention (PCI) than patients without COPD. Shown are all-cause mortality (A), cardiac mortality (B), and occurrence of myocardial infarction (C) after the index PCI. CHEST 2010 138, 621-627DOI: (10.1378/chest.10-0300) Copyright © 2010 The American College of Chest Physicians Terms and Conditions
Figure 2 Multivariate proportional hazard model showing COPD as an independent risk factor for various adverse outcomes in patients after percutaneous coronary intervention. DES = drug-eluting stent; LV EF = left ventricular ejection fraction; MI = myocardial infarction. See Figure 1 for expansion of other abbreviation. CHEST 2010 138, 621-627DOI: (10.1378/chest.10-0300) Copyright © 2010 The American College of Chest Physicians Terms and Conditions
Figure 3 Survival analysis of patients after PCI stratified based on the presence and severity of COPD. Patients without COPD are shown as “no COPD”; patients with available pulmonary function test results are classified according to the following standard clinical definitions: very severe COPD, an FEV1/FVC ratio ≤ 70 and an FEV1 ≤ 30% predicted; severe COPD, an FEV1/FVC ratio ≤ 70 and an FEV1 between 30% and 50% predicted; and mild-to-moderate COPD, an FEV1/FVC ratio ≤ 70 and an FEV1 ≤ 50% predicted. Patients with an FEV1/FVC ratio > 70 are classified as such irrespective of their FEV1. See Figure 1 for expansion of abbreviation. CHEST 2010 138, 621-627DOI: (10.1378/chest.10-0300) Copyright © 2010 The American College of Chest Physicians Terms and Conditions
Figure 4 Survival analysis of patients with COPD with an abnormal, nonspecific pattern on pulmonary function tests (FEV1/FVC ratio > 70) stratified by FEV1 > 80% predicted and an FEV1 < 80% predicted. CHEST 2010 138, 621-627DOI: (10.1378/chest.10-0300) Copyright © 2010 The American College of Chest Physicians Terms and Conditions