Diagnostic challenges in cornual epithelioid trophoblastic tumor

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Diagnostic challenges in cornual epithelioid trophoblastic tumor Feng-Ying Fang, Chiung-Ru Lai, Ming-Jie Yang, Beng-Shian Huang, Chih-Yao Chen, Yiu-Tai Li, Ming-Shyen Yen, Peng-Hui Peter Wang Taiwanese Journal of Obstetrics and Gynecology Volume 53, Issue 2, Pages 235-238 (June 2014) DOI: 10.1016/j.tjog.2014.03.002 Copyright © 2014 Terms and Conditions

Fig. 1 Transvaginal ultrasound scan revealed: (A) endometrium (EM) of 5.8 mm without an intrauterine pregnancy; and (B) a 6-cm right adnexal mass with an irregular margin. Taiwanese Journal of Obstetrics and Gynecology 2014 53, 235-238DOI: (10.1016/j.tjog.2014.03.002) Copyright © 2014 Terms and Conditions

Fig. 2 Operative findings included: (A) a 7-cm irregular white-colored lesion (ETT) at the right cornural area during laparoscopic surgery; (B) a clear identification of the right ovary (RO) and fallopian tube (tube) during laparoscopic surgery; (C) an irregular surface with focal white necrosis of the tumor during exploratory laparotomy; and (D) complete excision of the tumor during exploratory laparotomy. Taiwanese Journal of Obstetrics and Gynecology 2014 53, 235-238DOI: (10.1016/j.tjog.2014.03.002) Copyright © 2014 Terms and Conditions

Fig. 3 Pathologic findings were: (A) atypical monotonous trophoblastic tumor cells surrounded by necrosis during hematoxylin and eosin examination (×140); (B) diffusely positive cytokeratin and hydroxysteroid dehydrogenase 3B1, suggesting a trophoblastic origin (×56); (C) focally positive β-human chorionic gonadotropin (×140); and (D) focally positive p63 (×56), suggesting a chorionic type of intermediate trophoblasts. Taiwanese Journal of Obstetrics and Gynecology 2014 53, 235-238DOI: (10.1016/j.tjog.2014.03.002) Copyright © 2014 Terms and Conditions