Date of download: 10/28/2017 Copyright © ASME. All rights reserved. From: A Simulation Protocol for Exercise Physiology in Fontan Patients Using a Closed Loop Lumped-Parameter Model J Biomech Eng. 2014;136(8):081007-081007-13. doi:10.1115/1.4027271 Figure Legend: Closed-loop lumped-parameter network of the Fontan circulation. Rsubscript, Lsubscript, and Psubscript are labels for resistor components, inductor components, and nodal pressures, respectively.

Date of download: 10/28/2017 Copyright © ASME. All rights reserved. From: A Simulation Protocol for Exercise Physiology in Fontan Patients Using a Closed Loop Lumped-Parameter Model J Biomech Eng. 2014;136(8):081007-081007-13. doi:10.1115/1.4027271 Figure Legend: Exercise clinical data from nine Fontan patients. Plots show correlations of (a) normalized HR, and (b) normalized TVR, to exercise level expressed in MET.

Date of download: 10/28/2017 Copyright © ASME. All rights reserved. From: A Simulation Protocol for Exercise Physiology in Fontan Patients Using a Closed Loop Lumped-Parameter Model J Biomech Eng. 2014;136(8):081007-081007-13. doi:10.1115/1.4027271 Figure Legend: Flow diagram for computing resistance values in the LPN. Highlighted items represent lists of resistance values used to construct the final list of resistance values in the LPN for a simulation.

Date of download: 10/28/2017 Copyright © ASME. All rights reserved. From: A Simulation Protocol for Exercise Physiology in Fontan Patients Using a Closed Loop Lumped-Parameter Model J Biomech Eng. 2014;136(8):081007-081007-13. doi:10.1115/1.4027271 Figure Legend: Simulation results of two example patients at various exercise levels

Date of download: 10/28/2017 Copyright © ASME. All rights reserved. From: A Simulation Protocol for Exercise Physiology in Fontan Patients Using a Closed Loop Lumped-Parameter Model J Biomech Eng. 2014;136(8):081007-081007-13. doi:10.1115/1.4027271 Figure Legend: Model validation of (a) CO and (b) O2 extraction against clinical data. Points connected by lines are results of the same patient at different exercise levels.

Date of download: 10/28/2017 Copyright © ASME. All rights reserved. From: A Simulation Protocol for Exercise Physiology in Fontan Patients Using a Closed Loop Lumped-Parameter Model J Biomech Eng. 2014;136(8):081007-081007-13. doi:10.1115/1.4027271 Figure Legend: (a) Atrial activation function and (b) intrathoracic pressure waveform. Note that values of APith and Pithoffset are typically negative during natural, nonmechanically ventilated breathing.

Date of download: 10/28/2017 Copyright © ASME. All rights reserved. From: A Simulation Protocol for Exercise Physiology in Fontan Patients Using a Closed Loop Lumped-Parameter Model J Biomech Eng. 2014;136(8):081007-081007-13. doi:10.1115/1.4027271 Figure Legend: Comparison of (a) CO and (b) O2 extraction between simulation and Appendix B equation estimation for the two example patients at six MET levels