Photodynamic therapy using methylene blue in lung adenocarcinoma xenograft and hamster cheek pouch induced squamous cell carcinoma Bérengère Obstoy,

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Photodynamic therapy using methylene blue in lung adenocarcinoma xenograft and hamster cheek pouch induced squamous cell carcinoma Bérengère Obstoy, Mathieu Salaun, Pierre Bohn, Liana Veresezan, Richard Sesboué, Luc Thiberville Photodiagnosis and Photodynamic Therapy Volume 15, Pages 109-114 (September 2016) DOI: 10.1016/j.pdpdt.2016.03.003 Copyright © 2016 The Authors Terms and Conditions

Fig. 1 Histological slices from hamster’s cheek pouch after PDT (all animals were euthanatized on Day 15). A to C: squamous carcinomas after methylene blue-induced PDT; A/epithelial ulceration (X5 magnification); B/subepthelial fibrotic changes (X20); C/vascular necrosis (X20); D: modification of healthy control pouch after methylene blue-induced PDT showing inflammatory infiltrates with areas of liquefactive necrosis with pus formation and diffuse muscular alterations (X10). Photodiagnosis and Photodynamic Therapy 2016 15, 109-114DOI: (10.1016/j.pdpdt.2016.03.003) Copyright © 2016 The Authors Terms and Conditions