Dosimetric analysis of varying cord planning organ at risk volume in spine stereotactic body radiation therapy Dawn Owen, MD, PhD, Charles S. Mayo, PhD,

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Dosimetric analysis of varying cord planning organ at risk volume in spine stereotactic body radiation therapy Dawn Owen, MD, PhD, Charles S. Mayo, PhD, Limin Song, PhD, Kamran Ahmed, MD, Nadia Laack, MD, MSc, Kenneth Olivier, MD Advances in Radiation Oncology Volume 1, Issue 1, Pages 76-81 (January 2016) DOI: 10.1016/j.adro.2015.12.001 Copyright © 2016 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

Figure 1 Sample thecal sac 0-, 1-, and 2-mm structures with sample dose-volume histogram. Advances in Radiation Oncology 2016 1, 76-81DOI: (10.1016/j.adro.2015.12.001) Copyright © 2016 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

Figure 2 Sample cord 0-, 1-, 2-, 3-, 4-, 5-, 6-, and 7-mm structures with sample dose-volume histogram. Advances in Radiation Oncology 2016 1, 76-81DOI: (10.1016/j.adro.2015.12.001) Copyright © 2016 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

Figure 3 Determining thecal sac dose correlation with spinal cord expansion margin. EQ2Gy, equivalent dose in 2 Gy/fraction; Max(2), maximum dose in 2 Gy equivalent fractions to the spinal cord or thecal sac. Advances in Radiation Oncology 2016 1, 76-81DOI: (10.1016/j.adro.2015.12.001) Copyright © 2016 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions

Figure 4 Myelopathy risk per Sahgal et al and Mayo Clinic minimum EQD2 to thecal sac. 2GyEQ, dose in equivalent 2-Gy fractions; EQ2Gy, biologically equivalent dose in 2-Gy fractions. Advances in Radiation Oncology 2016 1, 76-81DOI: (10.1016/j.adro.2015.12.001) Copyright © 2016 The Authors on behalf of the American Society for Radiation Oncology Terms and Conditions