From: Gene Regulatory Control of Myocardial Energy Metabolism Predicts Postoperative Cardiac Function in Patients Undergoing Off-pump Coronary Artery Bypass.

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From: Gene Regulatory Control of Myocardial Energy Metabolism Predicts Postoperative Cardiac Function in Patients Undergoing Off-pump Coronary Artery Bypass Graft Surgery:Inhalational versusIntravenous Anesthetics Anesthes. 2007;106(3):444-457. Figure Legend: Fig. 4. Anesthetic-induced modulation of gene expression. Using fold changes in gene expression between T1 and T2, Gene Set Enrichment Analysis identified three major pathways, which were differentially regulated by sevoflurane (SEVO) and propofol (PROP). (  A  ) Fatty acid (FA) oxidation pathway. (  B  ) DNA-damage signaling pathway. (  C  ) Granulocyte colony-stimulating factor (G-CSF) survival pathway. The average fold change of all enriched transcripts in the respective pathways was calculated (table S3 on the Anesthesiology Web site). The individual  dots  represent changes in pathway activity of each patient.  Horizontal lines  indicate mean values.  Date of download: 10/28/2017 Copyright © 2017 American Society of Anesthesiologists. All rights reserved.

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