Pathology of osteoarthritis

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Diseases of musculoskeletal system. 4. Degenerative bone diseases Osteoarthritis.

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OSTEOARTHRITIS. Osteoarthritis (OA) is a common, degenerative disease, which is characterized by local degeneration of joint cartilage and new bone formation.

DEGENERATIVE JOINT DISEASE = OSTEOARTHRITIS. DEGENERATIVE JOINT DISEASE Degenerative joint disease is chracterized by: 1. pain 2. stiffness 3. loss of.

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Presentation transcript:

Pathology of osteoarthritis Pathology of osteoarthritis. The osteoarthritic joint is characterized by degradation and loss of the articular cartilage, thickening of the subchondral bone accompanied by formation of bone marrow lesions and cysts, osteophytes at the joint margins, variable degrees of synovitis with synovial hypertrophy, meniscal degeneration (knee), and thickening of the joint capsule. (Reproduced with permission from Loeser RF. Age-related changes in the musculoskeletal system and the development of osteoarthritis. Clin Geriatr Med. 2010;26(3):371-386.) Source: Osteoarthritis, Current Diagnosis & Treatment: Geriatrics, 2e Citation: Williams BA, Chang A, Ahalt C, Chen H, Conant R, Landefeld C, Ritchie C, Yukawa M. Current Diagnosis & Treatment: Geriatrics, 2e; 2014 Available at: http://accessmedicine.mhmedical.com/DownloadImage.aspx?image=/data/books/953/lan002_fig_26-01.gif&sec=53377128&BookID=953&ChapterSecID=53375650&imagename= Accessed: October 29, 2017 Copyright © 2017 McGraw-Hill Education. All rights reserved