Fig. 1 Underestimation and lack of sensitivity of T<sub>1</sub>-weighted fat-suppressed (FS) SPGR sequence in the assessment of BMLs. (A) Sagital T<sub>2</sub>-weighted.

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Fig. 1 Underestimation and lack of sensitivity of T<sub>1</sub>-weighted fat-suppressed (FS) SPGR sequence in the assessment of BMLs. (A) Sagital T<sub>2</sub>-weighted FS image depicts BMLs in the patellofemoral compartment (→) as well as in the proximal tibiofibular joint (▸). (B) Sagittal T<sub>1</sub>-weighted FS SPGR of the same knee obtained just after the acquisition of sagittal T<sub>2</sub>-weighted FS sequence shows relevant underestimation of the size of BML in the femoral trochlea (→), as well as lack of sensitivity, as the patellar BML could not be detected in such technique. Note that BMLs in the proximal tibiofibular joint are barely seen in SPGR. From: Comment on: Bone marrow lesions in people with knee osteoarthritis predict progression of disease and joint replacement: a longitudinal study Rheumatology (Oxford). 2011;50(5):996-997. doi:10.1093/rheumatology/ker006 Rheumatology (Oxford) | © The Author 2011. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For Permissions, please email: journals.permissions@oup.com