Telomeres in Stem Cell Research

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Presentation transcript:

Telomeres in Stem Cell Research Pearl Sutter Mentor: Dr. Jane Peppard

Stem Cells Stem Cells Somatic (Adult)

Stem Cells Stem Cells Somatic (Adult) Embryonic (ES)

Stem Cells Stem Cells Somatic (Adult) Embryonic (ES) Induced Pluripotent Stem Cells (iPS)

Stem Cells Stem Cells Regeneration Somatic (Adult) Embryonic (ES) Induced Pluripotent Stem Cells (iPS) Regeneration

Telomeres Telomere Telomerase Nucleic Acid Bases (TTAGGG) Replication- RNA Telomerase Telomerase Reverse Transcriptase (TERT) Telomerase RNA Component (TERC or TR)

How Telomeres and Stem Cells Relate

My Research Interests Alzheimer's Disease 6th leading cause of death in US No cure at the moment Possible cure with Stem Cells Large production of telomerase- ES Shortened Telomeres- Alzheimer’s

Bibliography http://learn.genetics.utah.edu/content/stemcells/quickref/ http://www4.utsouthwestern.edu/cellbio/shay-wright/intro/facts/sw_facts.html http://learn.genetics.utah.edu/content/chromosomes/telomeres/ http://www.ncbi.nlm.nih.gov/pubmed/21222203 http://www.nature.com/bjc/journal/v96/n7/full/6603671a.html http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp http://www.alz.org/alzheimers_disease_facts_and_figures.asp

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