Clostridium difficile

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Presentation transcript:

Clostridium difficile E. Ostrowski F2013 Modified by DYH Clostridium difficile http://media.npr.org/assets/img/2012/12/10/lawley2-c750a84d24486c7f37077709319139acc364e3f8.jpg

E. Ostrowski F2013 Modified by DYH General Facts http://www.cdiff-support.co.uk/images/cDiff-Factors-Large.jpeg Transmitted person to person fecal-orally It is G(+) and is an anaerobe It is a commensal flora of human intestines (about 2-5%) BUT still has pathogenicity; Enterotoxin A and Cytotoxin B- these target the Rho family of GTPase’s Extremely anti-biotic resistant The genome consists of a circular chromosome of 4,290,252 bp with a G+C content of 29.06%, and a circular plasmid of 7,881 bp with a G+C content of 27.9%. Spore forming http://www.cdiff-support.co.uk/images/cDiffLarge.jpeg