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From: Resveratrol Inhibits Uveal Melanoma Tumor Growth via Early Mitochondrial Dysfunction Invest. Ophthalmol. Vis. Sci.. 2008;49(4):1299-1306. doi:10.1167/iovs.07-1233 Figure Legend: Tumor regression after peritumor injection of resveratrol in the C918 xenograft model. (A) Tumor size before and after three injections of vehicle or 20 mg resveratrol. H&E-stained sections of vehicle-treated tumor (B), 20 mg resveratrol-treated tumor (C), and adjacent normal skin tissue in the resveratrol-treated condition (D). Insets: detail of area around black arrows. (B, inset) Mitotic body; (C, inset) apoptotic cells. (C, D, *) Necrotic area. (C, white arrow) Calcified cell; (D, white arrow) inflammatory cells. Date of download: 10/29/2017 The Association for Research in Vision and Ophthalmology Copyright © 2017. All rights reserved.